Organisation profile
Organisation profile
ITM is globally recognised for its expertise in Leishmania and leishmaniases, covering a broad research portfolio, from fundamental to operational research, spanning our three scientific departments (ITM Leishmania Centre).
Within the Department of Biomedical Sciences (DBS), research on Leishmania follows two main axes:
- Basic experimental research into the parasite’s adaptive skills, including genome instability’s role in environmental stress adaptation, molecular mechanisms of quiescence, and drug resistance and tolerance.
- Applied research on Leishmania’s evolutionary genetics in natural contexts and the molecular epidemiology of leishmaniasis.
The Unit of Experimental Parasitology was established in January 2025 to ensure the continuation of ongoing, state-of-the-art research on Leishmania. In addition to developing new lines of basic experimental research on adaptation mechanisms in Leishmania and related parasites, we build on the successful experimental research lines of the Unit of Molecular Parasitology.
Fingerprint
Collaborations and top research areas from the last five years
Profiles
-
Direct sequencing of Leishmania donovani from patients in Garissa County, Northern Kenya, reveals a newly emerging intra-specific hybrid genotype
Omwenga, V. K., Kimita, G., Matoke-Muhia, D., Ayieko, C., Masakhwe, C., Ibrahim, M. H., Heeren, S., Dujardin, J.-C., Monsieurs, P., Domagalska, M. A. & Waitumbi, J., Jan-2026, In: PLoS Neglected Tropical Diseases. 20, 1, 16 p., e0013144.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open Access -
From dogma to data: charting a path forward for clinico-immunological research in Ethiopian cutaneous leishmaniasis
Spatial CL Consortium, 16-Jan-2026, In: Infectious Diseases of Poverty. 15, 1, 10 p., 10.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Immunopeptidomics of cutaneous leishmaniasis patients reveals the natural antigenic landscape
de Vrij, N., Pepermans, E., Laurijssen, L., Pham, T.-T., Thijs, L., Boonen, K., Ramadan, K., Maes, I., Aleka, Y., Kassa, M., Mekonnen, T., Asres, M. S., Woldetensay, M., Hassen, S., Bialfew, F., Tilahun Zewdu, F., Abdela, S. G., Domagalska, M. A., Cuypers, B. & van Henten, S. & 5 others, , 20-Feb-2026, In: Frontiers in Immunology. 17, 15 p., 1765843.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open Access