Projects per year
The Protozoology Research Group is comprised of four research units performing basic and translational research on three major vector-borne protozoan parasites responsible for devastating diseases in humans and animals across the developing world: Leishmania (human leishmaniasis), Plasmodium (human malaria), Trypanosoma (human and animal African trypanosomiasis). Intensive control and elimination efforts are currently ongoing to eliminate visceral leishmaniasis in the Indian subcontinent, malaria in the three continents and HAT in Africa. Our research is closely connected to this as the acquired new knowledge and its translation into innovative tools for diagnosis and surveillance will enhance the ongoing disease-control/elimination programmes and their follow-up.
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Cellular, molecular and functional characterization of quiescence in Leishmania donovani, the etiological agent of visceral leishmaniasis
27/04/22 → …
Molecular basis for the potency and selectivity of DNDI-6690, a promising lead for the development of novel anti-leishmanial drugs
27/04/22 → …
Diagnostic performance of three rK39 rapid diagnostic tests and two direct agglutination tests for the diagnosis of visceral leishmaniasis in Southern IranRezaei, Z., Pourabbas, B., Kühne, V., Pourabbas, P. & Büscher, P., 2022, In : Journal of Tropical Medicine. 2022, p. 3569704
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile
Genomic and phenotypic characterization of experimentally selected resistant Leishmania donovani reveals a role for dynamin-1-like protein in the mechanism of resistance to a novel antileishmanial compoundHefnawy, A., Negreira, G., Jara, M., Cotton, J. A., Maes, I., D'Haenens, E., Imamura, H., Cuypers, B., Monsieurs, P., Mouchtoglou, C., De Winter, H., Pintelon, I., Timmermans, J-P., Berriman, M., Sanders, M., Martin, J., de Muylder, G., Dujardin, J-C., Sterckx, Y. G-J. & Domagalska, M. A., 2022, In : MBio. 13, 1, 15 p., e0326421.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile39 Downloads (Pure)
Leishmania RNA virus-1 is similarly detected among metastatic and non-metastatic phenotypes in a prospective cohort of American Tegumentary LeishmaniasisValencia, B. M., Lau, R., Kariyawasam, R., Jara, M., Ramos, A. P., Chantry, M., Lana, J. T., Boggild, A. K. & Llanos-Cuentas, A., 2022, In : PLoS Neglected Tropical Diseases. 16, 1, 14 p., e0010162.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile8 Downloads (Pure)