Projects per year
After completing her PhD in Genetics at the University of Barcelona, she spent two years as a Postdoctoral researcher at the University of São Paulo investigating P. vivax spleen evasion mechanisms, and 6 months at the Hospital of Tropical Medicine in Manaus. In 2007, she joined ISGlobal (Barcelona) and moved to Papua New Guinea IMR, where her research focused on molecular epidemiology aspects of malaria including drug resistance, host susceptibility and transmission.
In 2012 she moved to the Institute of Tropical Medicine in Antwerp where she is an Associate Professor and Head of the Malariology Unit.
At the Malariology Unit, we apply state-of-the-art molecular, ‘omic and cell technologies to study how parasites adaptation to the host environment is moderated at the genomic and transcriptomic level. Most of our studies are solidly grounded in field-research and epidemiological studies aiming to provide a bridge between in vitro and in vivo research. In this endeavor we count on a strong network of collaborations in Africa, South America, South-East Asia and Oceania. Our ultimate goal is to contribute to the development of tools and strategies for better malaria control and elimination.
Specific lines of research:
. Mechanism and regulation of P. vivax invasion by integration of genomic, transcriptomic and phenotypic data.
. Investigate the mechanisms, emergence and spread of drug resistance in malaria parasites and develop (NGS) platforms to support monitoring, evaluation and improvement of current strategies.
. Investigate the effect of host and environmental factors (host genetics, treatment, immunity and seasonality) in Plasmodium transmission.
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27/04/21 → …
Exposing the effect of host, parasite and immunoparasitological factors on Plasmodium falciparum gametocyte conversion
3/11/20 → …
A study of the Plasmodium vivax reticulocyte invasion pathways and ligand candidates, with special attention to the promising PvTRAg and PvRBP multigenic families.
11/04/19 → 10/04/23
SchistoSAM: A proof-of-concept trial to evaluate artesunate-mefloquine as a novel alternative treatment for schistosomiasis in African children
1/10/18 → 30/09/22
Project: Research Project
Chemoprotective antimalarial activity of P218 against Plasmodium falciparum: a randomized, placebo-controlled volunteer infection studyChughlay, M. F., El Gaaloul, M., Donini, C., Campo, B., Berghmans, P-J., Lucardie, A., Marx, M. W., Cherkaoui-Rbati, M. H., Langdon, G., Angulo-Barturen, I., Viera, S., Rosanas-Urgell, A., Van Geertruyden, J-P. & Chalon, S., 2021, In : American Journal of Tropical Medicine and Hygiene. 104, 4, p. 1348-1358 11 p.
Research output: Contribution to journal › A1: Web of Science-article
Genetic variation in the immune system and malaria susceptibility in infants: a nested case-control study in Nanoro, Burkina FasoNatama, H. M., Rovira-Vallbona, E., Krit, M., Guetens, P., Sorgho, H., Somé, M. A., Traoré-Coulibaly, M., Valéa, I., Mens, P. F., Schallig, H. D. F. H., Berkvens, D., Kestens, L., Tinto, H. & Rosanas-Urgell, A., 2021, In : Malaria Journal. 20, 1, 14 p., 94.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile1 Downloads (Pure)
High proportion of genome-wide homology and increased pre-treatment pvcrt levels in Plasmodium vivax late recurrences: a chloroquine therapeutic efficacy studyRovira-Vallbona, E., Van Hong, N., Kattenberg, J. H., Huan, R. M., Binh, N. T. H., Ngọc, N. T. H., Guetens, P., Hieu, N. L., Hien, N. T. T., Sang, V. T., Long, N. D., Sauve, E., Duong, T. T., Xuan Xa, N., Erhart, A. & Rosanas-Urgell, A., 2021, In : Antimicrobial Agents and Chemotherapy. 65, 8, p. e0009521 45 p.
Research output: Contribution to journal › A1: Web of Science-articleFile5 Downloads (Pure)
Rosanas-Urgell, A. & Gamboa, D., 2021, In : Malaria Journal. 20, 1, 13 p., 225.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile
Artemisinin exposure at the ring or trophozoite stage impacts Plasmodium falciparum sexual conversion differentlyPortugaliza, H. P., Miyazaki, S., Geurten, F. J., Pell, C., Rosanas-Urgell, A., Janse, C. J. & Cortés, A., 2020, In : eLIFE. 9, 22 p., e60058.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile2 Downloads (Pure)