Projects per year
Bart graduated as a Master in Biology: Cell & Systems Biology at the University of Antwerp in 2013. Currently he is a final year PhD Student in Systems Biology, Bio-informatics and Data Mining, holding an ‘Aspirant’ Fellowship of the FWO. He works in two research groups and combines the techniques of both. At one side he is member of the ADReM group (Advanced Database Research and Modelling) at the University of Antwerp and working under supervision of Prof. dr. Kris Laukens. Their research focusses on bio-informatics, data-mining and network biology with a vast variety of applications. Secondly, he is part of the Molecular Parasitology Unit (MPU) lead by Prof. dr Jean-Calaude Dujardin, located in the Institute of Tropical Medicine, Antwerp.
Specifically, Bart studies the parasite Leishmania donovani, which is responsible for the disease visceral leishmaniasis. Each year, over 5 million people contract this disease, which is lethal without treatment. His research focusses on unraveling developmental and drug-resistance mechanisms of the parasite by collecting (wet-lab, MPU) and integrating genomics, transcriptomics, proteomics and metabolomics data (ADReM).
Cell & Systems Biology, Master of Science
Junior Researcher, Department of Mathematics and Computer Sciences, University of Antwerp, Antwerp, Belgium.1-Oct-2013 → …
A framework to deduce the convoluted repertoire and epitope hierarchy of human T cell responses in visceral leishmaniasis: patient meets in silico
3/11/20 → …
A systems biology approach for a comprehensive understanding of development and adaptation in Leishmania donovani
22/10/13 → 23/05/18
& 90 others, , 2021, In : Nature Chemical Biology.
Research output: Contribution to journal › Article
Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIVAdriaensen, W., Cuypers, B., Cordero, C. F., Mengasha, B., Blesson, S., Cnops, L., Kaye, P. M., Alves, F., Diro, E. & van Griensven, J., 2020, In : EBioMedicine. 55, p. 102748
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile1 Downloads (Pure)
The absence of C-5 DNA methylation in Leishmania donovani allows DNA enrichment from complex samplesCuypers, B., Dumetz, F., Meysman, P., Laukens, K., De Muylder, G., Dujardin, J-C. & Domagalska, M. A., 2020, In : Microorganisms. 8, 8
Research output: Contribution to journal › A1: Web of Science-article
Host transcriptomic signatures as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIVAdriaensen, W., Cuypers, B., Cordero, F. C., Mengasha, B., Blesson, S., Cnops, L., Kaye, P., Alves, F., Diro, E. & Van Griensven, J., 2019, In : European Journal of Immunology. 49, p. 1193-1193 1 p.
Research output: Contribution to journal › Conference abstract in journal
A systems biology approach for a comprehensive understanding of molecular adaptation in Leishmania donovaniCuypers, B., 2018, Antwerp: University of Antwerp, Faculty of Pharmacy, Biomedical and Veterinary Sciences, Department of Biomedical Sciences. 198 p.
Research output: Thesis › Doctoral dissertation - Doctoral dissertation