Bart Cuypers

Molecular Parasitology

https://orcid.org/0000-0002-7198-1470

Phone+32(0)32476496
Emailbcuypers@itg.be

Nationalestraat 155
2000 Antwerp
Belgium

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Personal profile

Research expertise

Bart graduated as a Master in Biology: Cell & Systems Biology at the University of Antwerp in 2013. Currently he is a final year PhD Student in Systems Biology, Bio-informatics and Data Mining, holding an ‘Aspirant’ Fellowship of the FWO. He works in two research groups and combines the techniques of both. At one side he is member of the ADReM group (Advanced Database Research and Modelling) at the University of Antwerp and working under supervision of Prof. dr. Kris Laukens. Their research focusses on bio-informatics, data-mining and network biology with a vast variety of applications. Secondly, he is part of the Molecular Parasitology Unit (MPU) lead by Prof. dr Jean-Calaude Dujardin, located in the Institute of Tropical Medicine, Antwerp.

Specifically, Bart studies the parasite Leishmania donovani, which is responsible for the disease visceral leishmaniasis. Each year, over 5 million people contract this disease, which is lethal without treatment. His research focusses on unraveling developmental and drug-resistance mechanisms of the parasite by collecting (wet-lab, MPU) and integrating genomics, transcriptomics, proteomics and metabolomics data (ADReM).

Education/Academic qualification

Cell & Systems Biology, Master of Science

External positions

Junior Researcher, Department of Mathematics and Computer Sciences, University of Antwerp, Antwerp, Belgium.

1-Oct-2013 → …

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1 Finished
2 Active

A framework to deduce the convoluted repertoire and epitope hierarchy of human T cell responses in visceral leishmaniasis: patient meets in silico
De Vrij, N., van Griensven, J., Adriaensen, W., Laukens, K., Cuypers, B. & Cuypers, B.
3/11/20 → …
Project: PhD-project
A study of the Plasmodium vivax reticulocyte invasion pathways and ligand candidates, with special attention to the promising PvTRAg and PvRBP multigenic families.
De Meulenaere, K., Rosanas-Urgell, A., Laukens, K., Cuypers, B., Kattenberg, J. H. & Monsieurs, P.
11/04/19 → 10/04/23
Project: PhD-project
A systems biology approach for a comprehensive understanding of development and adaptation in Leishmania donovani
Cuypers, B., Dujardin, J., Dujardin, J. & Laukens, K.
22/10/13 → 23/05/18
Project: PhD-project

22 A1: Web of Science-article
1 A2: International peer reviewed article (not A1-type)
1 Comment/debate
1 Conference abstract in journal
More
- 1 Doctoral dissertation - Doctoral dissertation

A community resource for paired genomic and metabolomic data mining
Schorn, M. A., Verhoeven, S., Ridder, L., Huber, F., Acharya, D. D., Aksenov, A. A., Aleti, G., Moghaddam, J. A., Aron, A. T., Aziz, S., Bauermeister, A., Bauman, K. D., Baunach, M., Beemelmanns, C., Beman, J. M., Berlanga-Clavero, M. V., Blacutt, A. A., Bode, H. B., Boullie, A., Brejnrod, A. & 90 others, Bugni, T. S., Calteau, A., Cao, L., Carrión, V. J., Castelo-Branco, R., Chanana, S., Chase, A. B., Chevrette, M. G., Costa-Lotufo, L. V., Crawford, J. M., Currie, C. R., Cuypers, B., Dang, T., de Rond, T., Demko, A. M., Dittmann, E., Du, C., Drozd, C., Dujardin, J-C., Dutton, R. J., Edlund, A., Fewer, D. P., Garg, N., Gauglitz, J. M., Gentry, E. C., Gerwick, L., Glukhov, E., Gross, H., Gugger, M., Guillén Matus, D. G., Helfrich, E. J. N., Hempel, B-F., Hur, J-S., Iorio, M., Jensen, P. R., Kang, K. B., Kaysser, L., Kelleher, N. L., Kim, C. S., Kim, K. H., Koester, I., König, G. M., Leao, T., Lee, S. R., Lee, Y-Y., Li, X., Little, J. C., Maloney, K. N., Männle, D., Martin H, C., McAvoy, A. C., Metcalf, W. W., Mohimani, H., Molina-Santiago, C., Moore, B. S., Mullowney, M. W., Muskat, M., Nothias, L-F., O'Neill, E. C., Parkinson, E. I., Petras, D., Piel, J., Pierce, E. C., Pires, K., Reher, R., Romero, D., Roper, M. C., Rust, M., Saad, H., Saenz, C., Sanchez, L. M., Sørensen, S. J., Sosio, M., Süssmuth, R. D., Sweeney, D., Tahlan, K., Thomson, R. J., Tobias, N. J., Trindade-Silva, A. E., van Wezel, G. P., Wang, M., Weldon, K. C., Zhang, F., Ziemert, N., Duncan, K. R., Crüsemann, M., Rogers, S., Dorrestein, P. C., Medema, M. H. & van der Hooft, J. J. J., 2021, In : Nature Chemical Biology. 17, 4, p. 363-368 6 p.
Research output: Contribution to journal › Comment/debate
HLA-DRB1 alleles associated with lower leishmaniasis susceptibility share common amino acid polymorphisms and epitope binding repertoires
de Vrij, N., Meysman, P., Gielis, S., Adriaensen, W., Laukens, K. & Cuypers, B., 2021, In : Vaccines. 9, 3, 17 p., 270.
Research output: Contribution to journal › A1: Web of Science-article

Open Access
File
Sorted B cell transcriptomes point towards actively regulated B cell responses during ongoing chronic hepatitis B infections
Van Hees, S., Cuypers, B., Bourgeois, S., Groothuismink, Z. M. A., Meysman, P., Van der Vlies, P., de Knegt, R., Vonghia, L., Michielsen, P., Francque, S., Laukens, K., Boonstra, A. & Vanwolleghem, T., 2021, In : Cellular Immunology. 362, 8 p., 104283.
Research output: Contribution to journal › A1: Web of Science-article
APOL1 C-terminal variants may trigger kidney disease through interference with APOL3 control of actomyosin
Uzureau, S., Lecordier, L., Uzureau, P., Hennig, D., Graversen, J. H., Homble, F., Mfutu, P. E., Arcolino, F. O., Ramos, A. R., La Rovere, R. M., Luyten, T., Vermeersch, M., Tebabi, P., Dieu, M., Cuypers, B., Deborggraeve, S., Rabant, M., Legendre, C., Moestrup, S. K., Levtchenko, E. & 4 others, Bultynck, G., Erneux, C., Perez-Morga, D. & Pays, E., 2020, In : Cell Reports. 30, 11, p. 3821-3836/ e1–e13 29 p.
Research output: Contribution to journal › A1: Web of Science-article

Open Access
File
Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV
Adriaensen, W., Cuypers, B., Cordero, C. F., Mengasha, B., Blesson, S., Cnops, L., Kaye, P. M., Alves, F., Diro, E. & van Griensven, J., 2020, In : EBioMedicine. 55, 12 p., 102748.
Research output: Contribution to journal › A1: Web of Science-article

Open Access
File
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