Projects per year
Personal profile
Research expertise
Bart graduated as a Master in Biology: Cell & Systems Biology at the University of Antwerp in 2013. Currently he is a final year PhD Student in Systems Biology, Bio-informatics and Data Mining, holding an ‘Aspirant’ Fellowship of the FWO. He works in two research groups and combines the techniques of both. At one side he is member of the ADReM group (Advanced Database Research and Modelling) at the University of Antwerp and working under supervision of Prof. dr. Kris Laukens. Their research focusses on bio-informatics, data-mining and network biology with a vast variety of applications. Secondly, he is part of the Molecular Parasitology Unit (MPU) lead by Prof. dr Jean-Calaude Dujardin, located in the Institute of Tropical Medicine, Antwerp.
Specifically, Bart studies the parasite Leishmania donovani, which is responsible for the disease visceral leishmaniasis. Each year, over 5 million people contract this disease, which is lethal without treatment. His research focusses on unraveling developmental and drug-resistance mechanisms of the parasite by collecting (wet-lab, MPU) and integrating genomics, transcriptomics, proteomics and metabolomics data (ADReM).
Education/Academic qualification
Cell & Systems Biology, Master of Science
External positions
Junior Researcher, Department of Mathematics and Computer Sciences, University of Antwerp, Antwerp, Belgium.
1-Oct-2013 → …Fingerprint
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Projects
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A framework to deduce the convoluted repertoire and epitope hierarchy of human T cell responses in visceral leishmaniasis: patient meets in silico
De Vrij, N., van Griensven, J., Adriaensen, W., Laukens, K., Cuypers, B. & Cuypers, B.
3/11/20 → …
Project: PhD-project
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A systems biology approach for a comprehensive understanding of development and adaptation in Leishmania donovani
Cuypers, B., Dujardin, J., Dujardin, J. & Laukens, K.
22/10/13 → 23/05/18
Project: PhD-project
Research output
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A community resource for paired genomic and metabolomic data mining
Schorn, M. A., Verhoeven, S., Ridder, L., Huber, F., Acharya, D. D., Aksenov, A. A., Aleti, G., Moghaddam, J. A., Aron, A. T., Aziz, S., Bauermeister, A., Bauman, K. D., Baunach, M., Beemelmanns, C., Beman, J. M., Berlanga-Clavero, M. V., Blacutt, A. A., Bode, H. B., Boullie, A., Brejnrod, A. & 90 others, , 2021, In : Nature Chemical Biology.Research output: Contribution to journal › Article
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Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV
Adriaensen, W., Cuypers, B., Cordero, C. F., Mengasha, B., Blesson, S., Cnops, L., Kaye, P. M., Alves, F., Diro, E. & van Griensven, J., 2020, In : EBioMedicine. 55, p. 102748Research output: Contribution to journal › A1: Web of Science-article
Open AccessFile1 Downloads (Pure) -
The absence of C-5 DNA methylation in Leishmania donovani allows DNA enrichment from complex samples
Cuypers, B., Dumetz, F., Meysman, P., Laukens, K., De Muylder, G., Dujardin, J-C. & Domagalska, M. A., 2020, In : Microorganisms. 8, 8Research output: Contribution to journal › A1: Web of Science-article
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Host transcriptomic signatures as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV
Adriaensen, W., Cuypers, B., Cordero, F. C., Mengasha, B., Blesson, S., Cnops, L., Kaye, P., Alves, F., Diro, E. & Van Griensven, J., 2019, In : European Journal of Immunology. 49, p. 1193-1193 1 p.Research output: Contribution to journal › Conference abstract in journal
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A systems biology approach for a comprehensive understanding of molecular adaptation in Leishmania donovani
Cuypers, B., 2018, Antwerp: University of Antwerp, Faculty of Pharmacy, Biomedical and Veterinary Sciences, Department of Biomedical Sciences. 198 p.Research output: Thesis › Doctoral dissertation - Doctoral dissertation