Bouke de Jong

PhD, MD, MSc

Mycobacteriology

https://orcid.org/0000-0002-1017-4675

Phone+32(0)32476590
Emailbdejong@itg.be

Nationalestraat 155
2000 Antwerp
Belgium

Research activity per year

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Personal profile

Research expertise

Bouke de Jong completed her training in clinical infectious diseases at the Universities of Amsterdam, Nevada, and Stanford. Her focus on the molecular epidemiology of tuberculosis in San Francisco brought her to The Gambia, where she developed an interest in TB transmission and the M. tuberculosis complex member Mycobacterium africanum. After an MSc in epidemiology at the Netherlands Institute for Health Sciences and PhD at the University of Amsterdam, Dr. de Jong joined the Division of Infectious Diseases at New York University as Assistant Professor in 2007.

Since 2010 Dr. de Jong heads the Unit of Mycobacteriology at the Institute of Tropical Medicine. Besides tuberculosis, she studies Buruli Ulcer and leprosy, focusing on improved diagnostics and treatment, as well as molecular epidemiological studies on the impact of public health interventions to reduce transmission, for which she was supported by an ERC starting grant. Together with a very capable team she (co)supervises PhD students from different (endemic) countries.

Research lines

Improved molecular (resistance) diagnostics for leprosy, Buruli ulcer, and tuberculosis
Phylogeography, phylodynamics, and molecular epidemiology of M. ulcerans, M. tuberculosis, and M. leprae in the context of intervention studies
Optimized treatment for M. tuberculosis

Education/Academic qualification

Medicine, PhD

Medicine, MD

Epidemiology, MSc

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15 Active
25 Finished

Accurate diagnosis and effective treatment for tuberculosis retreatment patients in Niger
Souleymane Tiemogo, M. B., de Jong, B., Decroo, T., Rigouts, L., Mamadou, S. & Adehossi, E.
1/01/21 → 30/06/22
Project: PhD-project
Investigating drug tolerance in Mycobacterium tuberculosis
Goossens, S., de Jong, B. & Van Rie, A.
3/11/20 → …
Project: PhD-project
Innovative diagnostic and therapeutic measures to improve MDR-TB diagnosis and management in Conakry, Guinea
Hassane Harouna, S., de Jong, B., Decroo, T., Rigouts, L., Delamou, A. & Camara, L. M.
1/01/20 → …
Project: PhD-project
DeepMTB: Heteroresistance: an occult threat to the treatment success of resistant tuberculosis
de Jong, B. & Janssens, N.
Fonds voor Wetenschappelijk Onderzoek
1/01/20 → 31/12/23
Project: Research Project
Using novel molecular approaches to understand the transmission dynamics of Mycobacterium leprae in the Comoros
Braet, S., de Jong, B. & Rigouts, L.
11/04/19 → …
Project: PhD-project

112 A1: Web of Science-article
8 Letter
4 A2: International peer reviewed article (not A1-type)
3 Conference abstract in journal
More
- 1 Chapter
- 1 Editorial

Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs
Jouet, A., Gaudin, C., Badalato, N., Allix-Béguec, C., Duthoy, S., Ferré, A., Diels, M., Laurent, Y., Contreras, S., Feuerriegel, S., Niemann, S., André, E., Kaswa, M. K., Tagliani, E., Cabibbe, A., Mathys, V., Cirillo, D., de Jong, B. C., Rigouts, L. & Supply, P., 2021, In : European Respiratory Journal. 57, 3, 15 p., 2002338.
Research output: Contribution to journal › A1: Web of Science-article
Finding the right balance between efficacy and tolerability for TB treatment: the search continues
Maug, A. K. J., Hossain, M. A., Gumusboga, M., Decroo, T., Mulders, W., Braet, S., Buyze, J., Jiménez, D. A., Schurmans, C., Herssens, N., Demeulenaere, T., Lynen, L., de Jong, B. C. & Van Deun, A., 2021, In : International Journal of Tuberculosis and Lung Disease. 25, 1, p. 84-86 3 p.
Research output: Contribution to journal › A1: Web of Science-article

File

1 Downloads (Pure)
High rifampicin-resistant TB cure rates and prevention of severe ototoxicity after replacing the injectable by linezolid in early stage of hearing loss
Souleymane, M. B., Piubello, A., Lawan, I. M., Hassane-Harouna, S., Assao-Neino, M. M., Soumana, A., Hamidou-Harouna, Z., Gagara-Issoufou, A., Ortuño-Gutiérrez, N., Roggi, A., Schwoebel, V., Mamadou, S., Lynen, L., De Jong, B., Van Deun, A. & Decroo, T., 2021, In : European Respiratory Journal. 57, 1, 2002250.
Research output: Contribution to journal › A1: Web of Science-article
Human rights: finding the right balance for rifampicin-resistant TB treatment
Van Deun, A., Piubello, A., Lynen, L., de Jong, B. C. & Decroo, T., 2021, In : International Journal of Tuberculosis and Lung Disease. 25, 4, p. 327-328 2 p.
Research output: Contribution to journal › Letter

File

1 Downloads (Pure)
Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history
Coscolla, M., Gagneux, S., Menardo, F., Loiseau, C., Ruiz-Rodriguez, P., Borrell, S., Otchere, I. D., Asante-Poku, A., Asare, P., Sanchez-Buso, L., Gehre, F., Sanoussi, C. ND., Antonio, M., Affolabi, D., Fyfe, J., Beckert, P., Niemann, S., Alabi, A. S., Grobusch, M. P., Kobbe, R. & 9 others, Parkhill, J., Beisel, C., Fenner, L., Bottger, E. C., Meehan, C. J., Harris, S. R., de Jong, B. C., Yeboah-Manu, D. & Brites, D., 2021, In : Microbial Genomics. 7, 2, 14 p., 000477.
Research output: Contribution to journal › A1: Web of Science-article