Projects per year
Personal profile
Research expertise
Bouke de Jong completed her training in clinical infectious diseases at the Universities of Amsterdam, Nevada, and Stanford. Her focus on the molecular epidemiology of tuberculosis in San Francisco brought her to The Gambia, where she developed an interest in TB transmission and the M. tuberculosis complex member Mycobacterium africanum. After an MSc in epidemiology at the Netherlands Institute for Health Sciences and PhD at the University of Amsterdam, Dr. de Jong joined the Division of Infectious Diseases at New York University as Assistant Professor in 2007.
Since 2010 Dr. de Jong heads the Unit of Mycobacteriology at the Institute of Tropical Medicine. Besides tuberculosis, she studies Buruli Ulcer and leprosy, focusing on improved diagnostics and treatment, as well as molecular epidemiological studies on the impact of public health interventions to reduce transmission, for which she was supported by an ERC starting grant. Together with a very capable team she (co)supervises PhD students from different (endemic) countries.
Research lines
- Improved molecular (resistance) diagnostics for leprosy, Buruli ulcer, and tuberculosis
- Phylogeography, phylodynamics, and molecular epidemiology of M. ulcerans, M. tuberculosis, and M. leprae in the context of intervention studies
- Optimized treatment for M. tuberculosis
Education/Academic qualification
Medicine, PhD
Medicine, MD
Epidemiology, MSc
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Projects
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Accurate diagnosis and effective treatment for tuberculosis retreatment patients in Niger
Souleymane Tiemogo, M. B., de Jong, B., Decroo, T., Rigouts, L., Mamadou, S. & Adehossi, E.
1/01/21 → 30/06/22
Project: PhD-project
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Investigating drug tolerance in Mycobacterium tuberculosis
Goossens, S., de Jong, B. & Van Rie, A.
3/11/20 → …
Project: PhD-project
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DeepMTB: Heteroresistance: an occult threat to the treatment success of resistant tuberculosis
Fonds voor Wetenschappelijk Onderzoek
1/01/20 → 31/12/23
Project: Research Project
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Innovative diagnostic and therapeutic measures to improve MDR-TB diagnosis and management in Conakry, Guinea
Hassane Harouna, S., de Jong, B., Decroo, T., Rigouts, L., Delamou, A. & Camara, L. M.
1/01/20 → …
Project: PhD-project
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Using novel molecular approaches to understand the transmission dynamics of Mycobacterium leprae in the Comoros
Braet, S., de Jong, B. & Rigouts, L.
11/04/19 → …
Project: PhD-project
Research output
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Finding the right balance between efficacy and tolerability for TB treatment: the search continues
Maug, A. K. J., Hossain, M. A., Gumusboga, M., Decroo, T., Mulders, W., Braet, S., Buyze, J., Jiménez, D. A., Schurmans, C., Herssens, N., Demeulenaere, T., Lynen, L., de Jong, B. C. & Van Deun, A., 2021, In : International Journal of Tuberculosis and Lung Disease. 25, 1, p. 84-86 3 p.Research output: Contribution to journal › A1: Web of Science-article
File1 Downloads (Pure) -
A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
Ngabonziza, J. C. S., Loiseau, C., Marceau, M., Jouet, A., Menardo, F., Tzfadia, O., Antoine, R., Niyigena, E. B., Mulders, W., Fissette, K., Diels, M., Gaudin, C., Duthoy, S., Ssengooba, W., André, E., Kaswa, M. K., Habimana, Y. M., Brites, D., Affolabi, D., Mazarati, J. B. & 5 others, , 2020, In : Nature Communications. 11, 1, p. 2917Research output: Contribution to journal › A1: Web of Science-article
Open AccessFile -
Case report: dynamics of acquired fluoroquinolone resistance under standardized short-course treatment of multidrug-resistant tuberculosis
Semuto Ngabonziza, J. C., Van Deun, A., Migambi, P., Belamo, N. E., Théogène, D., Habimana, Y. M., Ushizimpumu, B., Mulders, W., Decroo, T., Affolabi, D., Supply, P., de Jong, B. C. & Rigouts, L., 2020, In : American Journal of Tropical Medicine and Hygiene. 103, 4, p. 1443-1446 4 p.Research output: Contribution to journal › A1: Web of Science-article
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Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension
Ofori-Anyinam, B., Riley, A. J., Jobarteh, T., Gitteh, E., Sarr, B., Faal-Jawara, T. I., Rigouts, L., Senghore, M., Kehinde, A., Onyejepu, N., Antonio, M., de Jong, B. C., Gehre, F. & Meehan, C. J., 2020, In : Tuberculosis. 120, 12 p., 101899.Research output: Contribution to journal › A1: Web of Science-article
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Deep amplicon sequencing for culture-free prediction of susceptibility or resistance to 13 anti-tuberculous drugs
Jouet, A., Gaudin, C., Badalato, N., Allix-Béguec, C., Duthoy, S., Ferré, A., Diels, M., Laurent, Y., Contreras, S., Feuerriegel, S., Niemann, S., André, E., Kaswa, M. K., Tagliani, E., Cabibbe, A., Mathys, V., Cirillo, D., de Jong, B. C., Rigouts, L. & Supply, P., 2020, In : European Respiratory Journal.Research output: Contribution to journal › A1: Web of Science-article