Projects per year
Personal profile
Research expertise
Bouke de Jong completed her training in clinical infectious diseases at the Universities of Amsterdam, Nevada, and Stanford. Her focus on the molecular epidemiology of tuberculosis in San Francisco brought her to The Gambia, where she developed an interest in TB transmission and the M. tuberculosis complex member Mycobacterium africanum. After an MSc in epidemiology at the Netherlands Institute for Health Sciences and PhD at the University of Amsterdam, Dr. de Jong joined the Division of Infectious Diseases at New York University as Assistant Professor in 2007.
Since 2010 Dr. de Jong heads the Unit of Mycobacteriology at the Institute of Tropical Medicine. Besides tuberculosis, she studies Buruli Ulcer and leprosy, focusing on improved diagnostics and treatment, as well as molecular epidemiological studies on the impact of public health interventions to reduce transmission, for which she was supported by an ERC starting grant. Together with a very capable team she (co)supervises PhD students from different (endemic) countries.
Research lines
- Improved molecular (resistance) diagnostics for leprosy, Buruli ulcer, and tuberculosis
- Phylogeography, phylodynamics, and molecular epidemiology of M. ulcerans, M. tuberculosis, and M. leprae in the context of intervention studies
- Optimized treatment for M. tuberculosis
Education/Academic qualification
Medicine, PhD
Medicine, MD
Epidemiology, MSc
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Collaborations and top research areas from the last five years
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THREE-G: The causes and consequences of historical contingencies in the evolution of extensively drug-resistant Mycobacterium tuberculosis
Gagneux, S., Ardizzoni, E., Rigouts, L. & de Jong, B.
1/01/25 → 31/12/28
Project: Research Project
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Rifampicin-Resistant Tuberculosis Treatment: Improve Safety while Safeguarding Success in Niger
Maman Lawan Sahirou, I., de Jong, B., Decroo, T., Lorent, N. & Ag Doutchi, M.
1/01/25 → …
Project: PhD-project
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ZLRM Pakistan: ZeroLeprosyRoadMap Pakistan (2)
Hasker, E., de Jong, B., Braet, S., Cloots, K., de Gooyer, T. & Shih, K.
Deutsche Lepra- und Tuberkulosehilfe
1/11/24 → 31/12/27
Project: Research Project
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STARLEP: Contribution of drug-resistance and M. lepromatosis to persistent leprosy transmission in parts of Africa
1/07/24 → 30/06/28
Project: Research Project
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TIFA DRC: Tuberculosis Implementation Framework Agreement
Rigouts, L., Gumusboga, M. & de Jong, B.
United States Agency for International Development
15/02/24 → 14/11/25
Project: Service
Research output
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70% ethanol preserves mycobacterial RNA from cultures more efficiently than GTC-TCEP
Krausser, L., Van Dyck-Lippens, M., Balde, R., Reenaers, R., Al Mubarak, R., Rigouts, L., Walter, N. D., Voskuil, M. I., Van Rie, A., de Jong, B. C. & Braet, S. M., 2025, In: Scientific Reports. 15, 1, 9 p., 12322.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Direct thin-layer agar for bedaquiline-susceptibility testing of Mycobacterium tuberculosis at BSL2 level yields high accuracy in 15 days from sputum processing
Cuella-Martin, I., Runyambo, D., De Bock, S., Diels, M., Niyompano, H., Hakizayezu, F., Keysers, J., De Rijk, WB., Habimana, YM., Gahamanyi, N., Ardizzoni, E., Muvunyi, CM., de Jong, BC., Ngabonziza, JCS. & Rigouts, L., 2025, (E-pub ahead of print) In: Journal of Clinical Microbiology. 11 p.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Is global health security worth 0.01% of our gross domestic product?
Ooms, G., Assefa, Y., Charalambous, S., Dah, T. T. E., Decoster, K., de Jong, B., Hensen, B., Komatsu, R., Magloire, N. H., Mitchell, E. M. H., Reyniers, T., Rosanas-Urgell, A., Tarrafeta-Sayas, M-B., Tinto, H., Whiteside, A. & Ravinetto, R., 14-May-2025, In: PLoS Global Public Health. 5, 5, p. e0004491Research output: Contribution to journal › Article › peer-review
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Onset of infectiousness explains differences in transmissibility across Mycobacterium tuberculosis lineages
Windels, EM., Agüí, CV., de Jong, BC., Meehan, CJ., Loiseau, C., Goig, GA., Zwyer, M., Borrell, S., Brites, D., Gagneux, S. & Stadler, T., 2025, In: Epidemics. 51, 10 p., 100821.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Oral regimens for Rifampin-resistant, Fluoroquinolone-susceptible Tuberculosis
Guglielmetti, L., Khan, U., Velásquez, GE., Gouillou, M., Abubakirov, A., Baudin, E., Berikova, E., Berry, C., Bonnet, M., Cellamare, M., Chavan, V., Cox, V., Dakenova, Z., de Jong, BC., Ferlazzo, G., Karabayev, A., Kirakosyan, O., Kiria, N., Kunda, M., Lachenal, N., & 22 others , 2025, In: New England Journal of Medicine. 392, 5, p. 468-482 15 p.Research output: Contribution to journal › A1: Web of Science-article › peer-review