Projects per year
Personal profile
Research expertise
Professor Bouke de Jong leads the Mycobacteriology Unit at the Institute of Tropical Medicine in Antwerp. A clinical infectious disease specialist, she has worked extensively on tuberculosis in high burden settings, with a focus on molecular epidemiology, diagnostics, and drug resistance. Her work on leprosy centers on molecular epidemiology and post-exposure prophylaxis. Her Unit serves as a WHO Supranational TB Reference Lab and houses the world’s largest M. tuberculosis strain collection. She also co-leads ITM’s Master’s in Tropical Medicine and a global course on drug-resistant TB.
Research lines
- Improved molecular (resistance) diagnostics for leprosy, Buruli ulcer, and tuberculosis
- Phylogeography, phylodynamics, and molecular epidemiology of M. ulcerans, M. tuberculosis, and M. leprae in the context of intervention studies
- Optimized treatment for M. tuberculosis
Education/Academic qualification
Medicine, PhD
Medicine, MD
Epidemiology, MSc
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Collaborations and top research areas from the last five years
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TEBULA: Telacebec to Control Buruli Ulcer and Leprosy in Africa
The European & Developing Countries Clinical Trials Partnership
1/06/25 → 31/05/29
Project: Research Project
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THREE-G: The causes and consequences of historical contingencies in the evolution of extensively drug-resistant Mycobacterium tuberculosis
Gagneux, S., Ardizzoni, E., Rigouts, L. & de Jong, B.
1/01/25 → 31/12/28
Project: Research Project
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Rifampicin-Resistant Tuberculosis Treatment: Improve Safety while Safeguarding Success in Niger
Maman Lawan Sahirou, I., de Jong, B., Decroo, T., Lorent, N. & Ag Doutchi, M.
1/01/25 → …
Project: PhD-project
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ZLRM Pakistan: ZeroLeprosyRoadMap Pakistan (2)
de Jong, B., Braet, S., Cloots, K., de Gooyer, T., Shih, K. & Hasker, E.
Deutsche Lepra- und Tuberkulosehilfe
1/11/24 → 31/12/27
Project: Research Project
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STARLEP: Contribution of drug-resistance and M. lepromatosis to persistent leprosy transmission in parts of Africa
1/07/24 → 30/06/28
Project: Research Project
Research output
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70% ethanol preserves mycobacterial RNA from cultures more efficiently than GTC-TCEP
Krausser, L., Van Dyck-Lippens, M., Balde, R., Reenaers, R., Al Mubarak, R., Rigouts, L., Walter, N. D., Voskuil, M. I., Van Rie, A., de Jong, B. C. & Braet, S. M., 2025, In: Scientific Reports. 15, 1, 9 p., 12322.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Advancing Mycobacterium leprae transmission research: Insights from the R2STOP fund
Palmeirim, MS., Geluk, A., de Jong, BC., Braet, SM., Macaluso, KR., Tufariello, JM., Lavania, M., Singh, I., Sharma, R., Singh, P. & Steinmann, P., 2025, In: PLoS Neglected Tropical Diseases. 19, 8, 10 p., e0013370.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
A Telacebec-shaped puzzle piece in the treatment of mycobacterial diseases
de Jong, B., 2025, In: American Journal of Respiratory and Critical Care Medicine. 211, 8, p. 1341-1342Research output: Contribution to journal › Editorial › peer-review
Open Access -
Bedaquiline, delamanid, linezolid, and clofazimine for rifampicin-resistant and fluoroquinolone-resistant tuberculosis (endTB-Q): an open-label, multicentre, stratified, non-inferiority, randomised, controlled, phase 3 trial
endTB-Q Clinical Trial Team, 2025, In: Lancet Respiratory Medicine. 13, 9, p. 809-820 12 p.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Direct thin-layer agar for bedaquiline-susceptibility testing of Mycobacterium tuberculosis at BSL2 level yields high accuracy in 15 days from sputum processing
Cuella-Martin, I., Runyambo, D., De Bock, S., Diels, M., Niyompano, H., Hakizayezu, F., Keysers, J., De Rijk, WB., Habimana, YM., Gahamanyi, N., Ardizzoni, E., Muvunyi, CM., de Jong, BC., Ngabonziza, JCS. & Rigouts, L., 2025, In: Journal of Clinical Microbiology. 63, 4, 11 p.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access