Projects per year
Personal profile
Research expertise
Emmanuel Bottieau graduated as Medical Doctor from the “Université Catholique de Louvain” in 1988. He followed the post-graduate course of Tropical Medicine in 1988-1989 and gained clinical experience in tropical medicine and international health working with Médecins Sans Frontières (MSF-Belgium) from 1989 to 1993. He obtained the master diploma in General Medicine in 1994 (“Université Catholique de Louvain”) and specialized in Internal Medicine from 1994 to 1999 (including one year of specialization in Infectious Diseases) at the “Université Libre de Bruxelles”. He joined the Department of Clinical Sciences of the Institute in 1999. Since then, he is involved in the clinical activities (consultations, ward supervision,…) at the outpatient department of the Institute and in the inpatient unit of Tropical and HIV Medicine in the “Universitair Ziekenhuis van Antwerpen”. In 2007 he obtained his PhD degree at the University of Antwerp with a thesis on fever after a stay in the tropics.He has been appointed as Associate Professor in November 2012 and leads the Unit of Tropical Diseases since then. His research activities have included operational research on HIV and malaria in Mozambique (within the projects “Rede Integrada I and II”, with capacity strengthening in HIV care as main objective), clinical and diagnostic studies in the tropics and in travel clinics, and industry-sponsored clinical trials. His main current research topics are (1) the integrated management (diagnosis-treatment) of febrile illness in the tropics and in travellers (2) the clinical management of Neglected Tropical Diseases, with a focus on cysticercosis, schistosomiasis, strongyloidiasis and filarial infection and (3) the clinical decision-making in complex syndromes (neurological disorders, febrile illness,...) in low-resource settings.Research activities in travel medicine are frequently conducted in collaboration with internetional networks of travel clinics such as GeoSentinel, TropNet,,..
Teaching expertise
Course director (since 2013) and teacher in the post-graduate course Clinical/biomedical Sciences of Tropical Diseases
Teacher in different other ITM courses:
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Master in international health (on tropical medicine, clinical decision-making, blood transfusion, travel medicine, humanitarian emergencies)
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Post-graduate course for nurses (on tropical medicine, clinical decision-making, humanitarian emergencies)
Master in disease control (on vector-borne diseases, tuberculosis,...)
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Short Course on Antiretroviral Treatment (SCART)
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Short Course on Research and Evidence-based Medicine (since 2009)
Teacher outside ITM
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Visiting Professor of the Gorgas Course of Clinical Tropical Medicine, University Cayetano Heredia, Lima, Peru (since 2012)
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Lecturer in the Summer Course Global Health Diagnostics, Mac Gill University, Montreal, Canada (2015)
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Lecturer in the Travel Course of the Swiss Tropical and Public Health Institute, Basel, Switzerland (2015)
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Lecturer in the «Cours Interuniversitaire d’Infectiologie et Microbiologie Clinique» ULB-UCL-ULG (since 2013)
Services expertise
Besides the reference consultations for tropical and travel-related pathology, Emmanuel Bottieau has been lecturing for years tropical medicine, travel medicine and clinical decision-making for different organizations (Médecins sans Frontières, Artsen Zonder Vakantie, Luxemburg Air Rescue, local groups of general practitioners and internists). He also provides expert advice to the Belgian authorities and the European Medicine Agency for the evaluation of new drugs and vaccines in the field of tropical medicine (malaria, human African trypanosomiasis, dengue, Ebola,…). He is member of different professional bodies in Belgium and abroad (Belgian Society of Infectiology and Clinical Microbiology; European Society of Clinical Microbiology and Infectious Diseases; International Society of Travel Medicine) and acts as Associated Editor for the Journal Clinical Microbiology and Infection. He is also one of the contact persons in Belgium for different international working groups on Chagas disease, cysticercosis, echinococcosis,…).
Education/Academic qualification
Clinical Research, PhD, Fever after a Stay in the Tropics, University of Antwerp
2000 → 2007
Award Date: 29-Jun-2007
Master
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Collaborations and top research areas from the last five years
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Improving the clinical management and facility-based surveillance of febrile illness in rural Guinea: a multidisciplinary approach
Kourouma, K., Bottieau, E., Vercauteren, K., Liesenborghs, L., Vlieghe, E. & Delamou, A.
1/01/23 → …
Project: PhD-project
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SchistoSAM: A proof-of-concept trial to evaluate artesunate-mefloquine as a novel alternative treatment for schistosomiasis in African children
Bottieau, E., Polman, K., Van Herrewege, Y., Rosanas-Urgell, A., Mbow, M., Cisse, B. & Bottieau, E.
1/10/18 → 31/12/24
Project: Research Project
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Strongyloides stercoralis in the non-endemic setting and beyond: an epidemiological, clinical, diagnostic and treatment challenge
Buonfrate, D., Bottieau, E. & Vlieghe, E.
3/11/21 → 31/08/23
Project: PhD-project
Research output
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Antimalarial artesunate-mefloquine versus praziquantel in African children with schistosomiasis: an open-label, randomized controlled trial
Bottieau, E., Mbow, M., Brosius, I., Roucher, C., Gueye, C. T., Mbodj, O. T., Faye, B. T., De Hondt, A., Smekens, B., Arango, D., Burm, C., Tsoumanis, A., Paredis, L., Van Herrewege, Y., Potters, I., Richter, J., Rosanas-Urgell, A., Cissé, B., Mboup, S. & Polman, K., 2024, In: Nature Medicine. 30, p. 130-137Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Assessing viral metagenomics for the diagnosis of acute undifferentiated fever in returned travellers: a multicenter cohort study
Camprubí-Ferrer, D., Tomazatos, A., Balerdi-Sarasola, L., Cobuccio, LG., Van Den Broucke, S., Horváth, B., Van Esbroeck, M., Martinez, MJ., Gandasegui, J., Subirà, C., Saloni, M., Genton, B., Bottieau, E., Cadar, D. & Muñoz, J., 2024, (E-pub ahead of print) In: Journal of Travel Medicine. 9 p., taae029.Research output: Contribution to journal › A1: Web of Science-article › peer-review
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Challenges in conducting efficacy trials for new COVID-19 vaccines in developed countries
Dal-Ré, R., Bottieau, E., Launay, O., Rosendaal, FR. & Schwarzer-Daum, B., 2024, (E-pub ahead of print) In: Clinical Trials. 5 p.Research output: Contribution to journal › A1: Web of Science-article › peer-review
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Chikungunya infection in returned travellers: results from the geosentinel network, 2005-2020
GeoSentinel Network, 2024, In: Journal of Travel Medicine. 31, 2, 8 p., taae005.Research output: Contribution to journal › A1: Web of Science-article › peer-review
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Consensus definitions in imported human schistosomiasis:a GeoSentinel and TropNet Delphi study
Tamarozzi, F., Mazzi, C., Antinori, S., Arsuaga, M., Becker, S. L., Bottieau, E., Camprubi-Ferrer, D., Caumes, E., Duvignaud, A., Grobusch, M. P., Jaureguiberry, S., Jordan, S., Mueller, A., Neumayr, A., Perez-Molina, JA., Salas-Coronas, J., Salvador, F., Tomasoni, LR., van Hellemond, JJ., Vaughan, S., & 6 others , 2024, In: Lancet Infectious Diseases. 24, 10, p. e627-e637 11 p.Research output: Contribution to journal › Review › peer-review