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20212025

Research activity per year

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  • RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I

    Kirchhoff, A., Herzner, A., Urban, C., Piras, A., Düster, R., Mahlberg, J., Grünewald, A., Schlee-Guimaraes, T., Ciupka, K., Leka, P., Bootz, R., Wallerath, C., Hunkler, C., de Regt, A., Kümmerer, B., Christensen, M., Schmidt, F., Lee-Kirsch, M., Günther, C. & Kato, H. & 5 others, Bartok, E., Hartmann, G., Geyer, M., Pichlmair, A. & Schlee, M., Feb-2025, In: Embo Journal. 44, 3, p. 824-853 30 p.

    Research output: Contribution to journalA1: Peer-reviewed journal articlespeer-review

    Open Access
  • Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release

    Rösing, S., Ullrich, F., Meisterfeld, S., Schmidt, F., Mlitzko, L., Croon, M., Nattrass, R., Eberl, N., Mahlberg, J., Schlee, M., Wieland, A., Simon, P., Hilbig, D., Reuner, U., Rapp, A., Bremser, J., Mirtschink, P., Drukewitz, S., Zillinger, T. & Beissert, S. & 5 others, Paeschke, K., Hartmann, G., Trifunovic, A., Bartok, E. & Günther, C., 2024, In: Nature Communications. 15, 1, 15 p., 1534.

    Research output: Contribution to journalA1: Peer-reviewed journal articlespeer-review

    Open Access
  • A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA

    de Regt, A., Anand, K., Ciupka, K., Bender, F., Gatterdam, K., Putschli, B., Fusshöller, D., Hilbig, D., Kirchhoff, A., Hunkler, C., Wolter, S., Grünewald, A., Wallerath, C., Schuberth-Wagner, C., Ludwig, J., Paeschke, K., Bartok, E., Hagelueken, G., Hartmann, G. & Zillinger, T. & 2 others, Geyer, M. & Schlee, M., 2023, In: Nucleic Acids Research. 51, 21, p. 11893-11910 18 p.

    Research output: Contribution to journalA1: Peer-reviewed journal articlespeer-review

    Open Access
  • Chronic ER stress promotes cGAS/mtDNA-induced autoimmunity via ATF6 in myotonic dystrophy type 2

    Rösing, S., Ullrich, F., Meisterfeld, S., Schmidt, F., Mlitzko, L., Croon, M., Eberl, N., Schlee, M., Hilbig, D., Reuner, U., Rapp, A., Mirtschink, P., Drukewitz, S., Zillinger, T., Beissert, S., Paeschke, K., Hartmann, G., Trifunovic, A., Bartok, E. & Günther, C., 2023, In: Journal of Investigative Dermatology. 143, 11, p. S363-S363 1 p., 182.

    Research output: Contribution to journalMeeting abstract in journal

  • Influenza A infection stimulates RIG-I and enhances effector function of primary human NK cells

    Mohamed, A. A., Soler, S., Wegner, J., Bartok, E., Stankovic, S., Brooks, A. G. & Schlee, M., 2023, In: International Journal of Molecular Sciences. 24, 15, 16 p., 12220.

    Research output: Contribution to journalA1: Peer-reviewed journal articlespeer-review

    Open Access