Projects per year
Personal profile
Research expertise
Johan van Griensven (°1972), Medical Doctor (KU Leuven Belgium 1997), Internal Medicine specialist (KU Leuven 2004), PhD Medical Sciences: “Gene therapy of AIDS: Gene transfer of Antiretroviral Genes into Hematopoietic Stem Cells Using HIV-Derived Vectors” (Rega Institute, KU Leuven 2003; FWO scholarship), Masters in Epidemiology, London School of Hygiene and Tropical Medicine, 2010).
Between 2004 and 2014, he was based as clinician and researcher in Africa (including three years with Médecins Sans Frontières) and Asia (Cambodia). In 2008, he joined ITM with a post-doctoral grant from the Baillet Latour Foundation, to launch clinical research on neglected tropical diseases and their interaction with HIV. Since 2015, he heads the unit of Neglected Tropical Diseases at ITM.
His main field of interest is visceral leishmaniasis (VL) and HIV co-infection, with clinical trials and nested laboratory studies conducted in Ethiopia. He has a track record in leading scientific projects in complex settings, beyond leishmaniasis. During the 2013-2016 Ebola outbreak in West-Africa, he led a large consortium conducting a phase II/III clinical trial on convalescent plasma as treatment for Ebola virus disease in Guinea (H2020 funding; http://www.ebolatx.eu/). He co-launched the ITM outbreak research team and is currently member of the outbreak research team’s steering committee.
He currently is the course director of the short course in clinical research and evidence based medicine (SCREM course https://edu.itg.be/Course/Component/117?typeId=3)
He has published in high impact scientific journals including New England Journal of Medicine (n=3), Nature (n=1), Lancet (n=4) and Lancet Infectious Diseases (n=9). In 2017, he received the Dubois-Briguez price for research in tropical medicine.
Five key publications
1. Combination therapy for visceral leishmaniasis. J. van Griensven, M. Balasegaram, F Meheus, et al. Lancet Infectious Diseases 2010; 10: 184-94 [JIF: 25.2]
2. HIV-1 protease inhibitors for treatment of visceral leishmaniasis in HIV-co-infected individuals. J. van Griensven, E. Diro, R. Lopez-Velez, et al . Lancet Infectious Diseases 2013; 13: 251-9 [JIF: 25.2]
3. Immunomodulatory therapy of visceral leishmaniasis in HIV coinfected patients.W. Adriaensen W, TPC. Dorlo, G. Vanham, L Kestens, PM Kaye, J. van Griensven. Frontiers in Immunology 2018; 8: 1943 [JIF: 5.5]
4. Long-term clinical outcomes in visceral leishmaniasis-HIV co-infected patients during and after pentamidine secondary prophylaxis in Ethiopia: a single-arm clinical trial. E. Diro, K. Ritmeijer, M. Boelaert, F. Alves, R. Mohammed, C. Abongomera, R. Ravinetto, M. De Crop, H. Fikre, C. Adera, H. van Loen, A. Tsoumanis, W. Adriaensen, A. Hailu, J. van Griensven. Clinical Infectious Diseases 2018 66: 444-451 [JIF: 9.1]
5. Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea. J. van Griensven, T. Edwards, X. de Lamballerie, et al. for the Ebola-Tx Consortium. New England Journal of Medicine 2016; 374: 33-42 [JIF: 79.3]
Education/Academic qualification
PhD
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Enhancing the effectiveness and accessibility of treatment for cutaneous leishmaniasis in Ethiopia
Woge, M. T., van Griensven, J., Pareyn, M., Berens-Riha, N., Berens-Riha, N., Wegayehu, T. & Wendemagegn, Y.
1/01/25 → …
Project: PhD-project
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Assessing the burden and improving the diagnosis and clinical management of hyperreactive malarial splenomegaly patients in Northwest Ethiopia
Asres, M. S., Bottieau, E., van Griensven, J., Kassahun, A., Diro, E. & Berens-Riha, N.
1/01/25 → …
Project: PhD-project
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Quality assurance and decentralized diagnosis of cutaneous leishmaniasis and other common skin diseases in Ethiopia
Abate, D. T., van Griensven, J., Pareyn, M., Van Geertruyden, J. & Hailu, A.
29/05/24 → …
Project: PhD-project
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Bartonella quintana as a neglected cause of febrile illness and endocarditis in low-resource settings
Boodman, C., van Griensven, J. & Van Puyvelde, S.
8/06/23 → …
Project: PhD-project
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AIM-CL: Antimicrobial adjuvants to revert the Imbalance of skin Microbiota for improved outcomes of Cutaneous Leishmaniasis treatment in Ethiopia
van Griensven, J., Pareyn, M., Monsieurs, P., van Henten, S., Van Herrewege, Y., Van Herrewege, Y., van Henten, S., Monsieurs, P. & Pareyn, M.
Flemish Government - Department of Work, Economy, Science, Innovation
1/01/23 → 31/12/26
Project: Research Project
Research output
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Evidence of Coxiella burnetii and Bartonella species infections among patients with persistent febrile illness in four low- and middle-income countries
Boodman, C., Edouard, S., van Griensven, J., Koirala, K. D., Khanal, B., Rijal, S., Bhattarai, N. R., El Safi, S., Phe, T., Lim, K., Lutumba, P., Chappuis, F., Yansouni, C. P., Barbé, B., van Esbroeck, M., Verdonck, T., Boelaert, M., Fournier, P-É. & Bottieau, E., 6-May-2025, (E-pub ahead of print) In: Clinical Microbiology and Infection.Research output: Contribution to journal › Article › peer-review
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No distinct cytokine, chemokine, and growth factor blood profile associated with Monkeypox virus clade IIb infected patients
Bangwen, E., Berens-Riha, N., de Vrij, N., Ceulemans, A., Brosius, I., De Vos, E., Pham, TT., Bottieau, E., van Griensven, J., Netongo, PM., Van Esbroeck, M., Vercauteren, K., Van Dijck, C., Adriaensen, W. & Liesenborghs, L., 2025, In: Journal of Medical Virology. 97, 4, 11 p., e70320.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Unveiling the hidden burden: Exploring the psychosocial impact of cutaneous leishmaniasis lesions and scars in southern Ethiopia
Merdekios, B., Shewangizaw, M., Sappo, A., Ewunetu, E., van Griensven, J., van Geertruyden, JP., Ceuterick, M. & Bastiaens, H., 2025, In: PLoS ONE. 20, 2, 20 p., e0317576.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
A preliminary indication that HLA-A*03:01 may be associated with visceral leishmaniasis development in people living with HIV in Ethiopia
de Vrij, N., Vandoren, R., Ramadan, K., Van Hul, A., Ceulemans, A., Kassa, M., Melkamu, R., Yeshanew, A., Bogale, T., Beyene, H., Sisay, K., Kibret, A., Mersha, D., Cuypers, WL., Vogt, F., van Henten, S., Ritmeijer, K., Pham, TT., Meysman, P., Laukens, K., & 5 others, 2024, In: PLoS Neglected Tropical Diseases. 18, 9, 17 p., e0012000.Research output: Contribution to journal › A1: Web of Science-article › peer-review
Open Access -
Bartonella quintana detection among arthropods and their hosts: a systematic review and meta-analysis
Boodman, C. G., Gupta, N., van Griensven, J. & Van Bortel, W., 2024, In: Parasites and Vectors. 17, 1, 328.Research output: Contribution to journal › Review › peer-review
Open Access