Projects per year
Personal profile
Research expertise
Kevin K. Ariën (born 1978) graduated as a Master in Biomedical Sciences from the Vrije Universiteit Brussel (VUB) in 2001 and obtained a PhD in virology in 2005 from the University of Antwerp for his work on HIV replicative fitness at the Institute of Tropical Medicine Antwerp (ITM) and the Case Western Reserve University, Cleveland, Ohio. He then continued with a postdoctoral stint at Tibotec-Virco (2005-2006) and as an FWO Postdoctoral Fellow at Ghent University (2006-2009) before returning to the Institute of Tropical Medicine Antwerp in late 2009.
For about a decade, Dr. Ariën’s research in the field of HIV focused on replicative fitness, understanding biological mechanisms of sexual transmission and prevention through topical microbicides. In 2014, he started a new research program on emerging arthropod-borne (arbo) viruses, with a particular interest in Chikungunya virus and in June 2014 he was appointed head of ITM’s Virology Unit, director of the Virus BSL3 facility and Professor of Virology. Dr. Ariën is one of the founding members of the Outbreak Research Team and the Insectary Core at ITM. Since 2020, he is co-director of the WHO Collaborating Centre for HIV/AIDS Diagnostics and Laboratory Support (BEL-27). Starting 2022, Dr. Ariën was appointed as head of the department of Biomedical Sciences at ITM.
In the context of the 2014-2016 Ebola epidemic in West Africa, the Unit developed Ebola virus diagnostic testing at ITM, as part of the National Reference Center for Tropical Infectious Diseases. His current research efforts include the development of new diagnostic tools for the detection of a wide variety of (re-)emerging viruses, including epidemiologically relevant arboviruses and haemorrhagic fever viruses. A more basic research program focuses on virus-host-vector molecular interactions of chikungunya and dengue virus and identifying sylvatic reservoirs of arboviruses. The Unit has active collaborations in Peru, Cuba, and DR Congo on the field application of new diagnostic tests, studying arbovirus-host interactions and sylvatic reservoirs of (re-)emerging viruses. Early 2020, the unit invested a significant part of its capacity on SARS-CoV-2 research, incl. setting up diagnostic methods, studies on the duration of immune responses following natural infection and vaccination, and re-infection.
Dr. Ariën serves as scientific adviser to the National Ebola Coordinator and as a technical expert for viral diagnostics to the Belgian Federal Agency for Medicines and Health Products. He regularly serves on review panels of the National Research Foundation of South Africa (NRF) and Flanders Innovation and Entrepreneurship, and he received the Year Prize for Science Communication in 2015 from the Royal Flemish Academy of Belgium for Science and the Arts. Dr. Ariën is Editorial Board member of Frontiers in Immunology and PLOS ONE.
Kevin K. Ariën is also appointed as Professor in the department of Biomedical Sciences of the Faculty of Pharmaceutical, Biomedical and Veterinary Sciences at the University of Antwerp, where he teaches general Virology, Molecular Virology and Infections, and Pathogenesis and clinical aspects of tropical infectious diseases.
Education/Academic qualification
PhD, University of Antwerp
MSc, Vrije Universiteit Brussel
External positions
Professor, University of Antwerp
1-Oct-2019 → …
Keywords
- B510-infections
- HIV
- Chikungunya virus
- Ebola virus
- arboviruses
- dengue
- SARS-CoV-2
- COVID-19
- virology
- Zika
- virus-host-vector interactions
- B780-tropical-medicine
- virology
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Collaborations and top research areas from the last five years
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Holistic antibody determination of Ebola booster vaccination: impact of schedule, dose and prevalent co-infections
Oostvogels, S. (PhD Student), Adriaensen, W. (Promotor), Ariën, K. (Promotor) & Ariën, K. (Promotor)
26/05/26 → …
Project: PhD-project
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NS1-CAPFLAVI: Development of NS1 antigen-CAPture assays for accurate diagnosis of neurotropic FLAVIviruses
Ariën, K. (Promotor), Ariën, K. (Promotor) & Delputte, P. (Promotor)
1/01/26 → 31/12/26
Project: Research Project
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saRplix: Optimization of self-amplifying RNA and mRNA production and formulation through advanced microfluidics
Ariën, K. (Promotor) & Bartholomeeusen, K. (PI)
1/10/25 → 30/09/29
Project: Research Project
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RiVAc: RNAi based Vaccine development in the Aedes albopictus mosquito against chikungunya virus
Ariën, K. (Promotor), Bartholomeeusen, K. (PI), Müller, R. (CoPI), Brustolin, M. (CoPI) & Janssens, E. (PhD Student)
Flemish Government - Department of Work, Economy, Science, Innovation
1/01/25 → 31/12/28
Project: Research Project
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A novel singlet oxygen-based photoelectrochemical diagnostic tool for dengue detection
Op de Beeck, H. (PhD Student), Ariën, K. (Promotor), De Wael, K. (Promotor) & Verbruggen, S. (Promotor)
14/11/24 → …
Project: PhD-project
Research output
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Assessing the diagnostic performance of clinical, serological and molecular approaches to improve dengue case detection in the Peruvian Amazon
Hauner, A., Aroni Sierra, J., Merino, X., Villa, C., Torres, F., Lagatie, O., Talledo, M., Arien, K. K. & Falconi-Agapito, F., Feb-2026, In: PLoS Neglected Tropical Diseases. 20, 2, 22 p., e0013984.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open Access -
Better diagnostics could have limited this Ebola outbreak
Ariën, K. K., Jun-2026, In: Nature. 654, 8117, p. 9Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
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Dengue antibody dynamics resolved at epitope level using a dengue 1 human infection model
Bouckaert, J., Waickman, A. T., Thomas, S. J., Ariën, K. K. & Lagatie, O., 9-Jun-2026, In: International Journal of Infectious Diseases. 169, 9 p., 108771.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open Access -
Development and validation of a sample-to-result real time multiplex RT-PCR test for human African trypanosomiasis and arboviral febrile illnesses in the Democratic Republic of the Congo
Hauner, A., Lusala, S. M., Rogé, S., Van Reet, N., Cnops, L., Da Luz, R. I., Van Esbroeck, M., Kapandji, M., Kuamfumu, M. M., Kiabanzawoko, O., Phanzu, D. M., Verlé, P., Ahuka-Mundeke, S. & Ariën, K. K., 5-Feb-2026, In: BMC Infectious Diseases. 26, 1, 513.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open Access -
Enhanced immune responses to mRNA compared with adenoviral vector COVID-19 vaccines during pregnancy: implications for pandemic preparedness
De Brabandere, L., Herzog, S. A., Desombere, I., Arien, K. K., Olislagers, V., Georges, D., Dauby, N., Vercoutere, A., Goossens, M., Pannus, P., Leuridan, E., Marchant, A. & Maertens, K., 15-Feb-2026, In: Vaccine. 73, 10 p., 128153.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Activities
- 2 Editor of research journal
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Aids Research and Therapy (Journal)
Ariën, K. (Editor)
Jan-2016 → …Activity: Publication peer-review and editorial work types › Editor of research journal
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PLOS ONE (Journal)
Ariën, K. (Editor)
1-Aug-2016Activity: Publication peer-review and editorial work types › Editor of research journal