Projects per year
Personal profile
Research expertise
Luc Kestens graduated as a Master in Biology in 1978 from the University of Antwerp.
He joined the Laboratory of Pathology and experimental schistosomiasis of ITM in the same year and prepared a PhD thesis on the immunopathology of immune complexes in murine experimental schistosomiasis which he defended in 1987. Because his interest in immunology, he became involved in HIV research since the early days of the HIV pandemic in 1983. In 1985, he was the first to publish the lack of association between HIV and the endemic form of Kaposi’s Sarcoma in Eastern Africa.
Since 1985, his main research focus was the immunopathogenesis of HIV published more than one hundred twenty scientific papers in international scientific journals. He became lecturer in Immunology at ITM in 1998, was appointed head of the laboratory of Immunology in 1995, and was elected chairman of the Department of Microbiology in 2000. He supervises several undergraduate students, Master and PhD students.
Luc Kestens is professor at ITM and professor in immunology of tropical infectious diseases of the University of Antwerp. He serves in scientific committees of the Flemish Institute of Science and Technology (IWT) and the Flemish Flemish Interuniversity Council (VLIR). He is expert consultant of Belgian Institute of Public Health (ISP-WIV) and consultant for international organizations such as the WHO. His lab is part of the WHO Collaborating Centre for HIV/AIDS Diagnostic and Laboratory Support, in particular CD4 counting.
Research lines
- The immunological cause for resistance against HIV-infection.
- Immunological monitoring of HIV infection and immune reconstitution.
- The immunopathogenesis of the immune reconstitution inflammatory syndrome (IRIS) in HIV patients.
- Alternatives for immunological monitoring of HIV infection in development countries.
Education/Academic qualification
Master
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Projects
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The role of T cell diversity in the pathogenesis of TB-IRIS in HIV/aids patients in Uganda
Nakiwala, J., Kestens, L. & Pala, P.
1/07/11 → …
Project: PhD-project
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A study of the mechanisms of natural killer cell-mediated resistance to HIV-infection
Hens, J., Kestens, L. & Kestens, L.
22/01/15 → 2/04/20
Project: PhD-project
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Study of the dynamics, phenotype and role of regulatory T cells during HIV subtype C early Infecton and during prime-boost vaccination with HIVIS-DNA
Matavele Chissumba, R., Kestens, L. & Jani, I. V.
1/12/13 → 8/05/19
Project: PhD-project
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SeTPAT: A Directed Search for a Treponema pallidum Antigen Test
Kenyon, C., Büscher, P., Kestens, L., Ravinetto, R., Van Ostade, X. & Ratsarahery, L.
Flemish Government - Department of Economy, Science & Innovation
1/07/13 → 28/02/19
Project: Research Project
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The role of TH17 and regulatory T-cells in the development of schistosoma pathology in Senegal
Mbow, M., Polman, K., Kestens, L., Mboup, S. & Yazdanbakhsh, M.
1/01/12 → 11/04/19
Project: PhD-project
Research output
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Genetic variation in the immune system and malaria susceptibility in infants: a nested case-control study in Nanoro, Burkina Faso
Natama, H. M., Rovira-Vallbona, E., Krit, M., Guetens, P., Sorgho, H., Somé, M. A., Traoré-Coulibaly, M., Valéa, I., Mens, P. F., Schallig, H. D. F. H., Berkvens, D., Kestens, L., Tinto, H. & Rosanas-Urgell, A., 2021, In : Malaria Journal. 20, 1, p. 94Research output: Contribution to journal › A1: Web of Science-article
Open AccessFile -
Lack of elevated pre-ART elastase-ANCA levels in patients developing TB-IRIS
TB-IRIS Study Group, 2020, In : PLoS ONE. 15, 12, p. e0244800Research output: Contribution to journal › A1: Web of Science-article
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Complement receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes
Prajapati, S. K., Borlon, C., Rovira-Vallbona, E., Gruszczyk, J., Menant, S., Wai-Hong Tham, Kattenberg, J. H., Villasis, E., De Meulenaere, K., Gamboa, D., Vinetz, J., Fujita, R., Xa Nguyen Xuan, Ferreira, M. U., Nino, C. H., Patarroyo, M. A., Spanakos, G., Kestens, L., Van Den Abbeele, J. & Rosanas-Urgell, A., 2019, In : Scientific Reports. 9, 1, p. 8943 13 p., 8943.Research output: Contribution to journal › A1: Web of Science-article
Open AccessFile3 Downloads (Pure) -
Determination of HSV-2-specific cellular responses by IFN-gamma ELISpot assay in HIV-1 heterosexual discordant couples in Dakar, Senegal
Camara, M., Padane, A., Seye, B. J. K., Diaw, P. A., Kestens, L., Mboup, S., Boye, C. S. B. & Dieye, N. T., 2019, In : European Journal of Immunology. 49, p. 1061-1061 1 p.Research output: Contribution to journal › Conference abstract in journal
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Increased KLRG1 and PD-1 expression on CD8 T lymphocytes in TB-IRIS
TB-IRIS Study Grp, 2019, In : PLoS ONE. 14, 4, p. e0215991 15 p., 0215991.Research output: Contribution to journal › A1: Web of Science-article
File2 Downloads (Pure)