Personal profile
Research expertise
Pieter Monsieurs is a senior scientist in Computational Biology at the Institute of Tropical Medicine (ITM), where he has been active since October 2019. His current research focuses on the analysis and integration of high-throughput sequencing data to address biological questions in protozoan pathogens, with a particular emphasis on population genomics, single-cell genomics and transcriptomics. His recent work contributes to a growing body of publications in these areas, supporting research across multiple ITM units, including the Trypanosoma unit (Prof. J. Van Den Abbeele), the Unit of Malariology (Prof. Anna Rosanas-Urgell), and the Unit of Molecular Parasitology (Prof. J.C. Dujardin).
In his recent publications, he applies advanced computational and statistical approaches to genomic, transcriptomic and single-cell data to study parasite diversity, adaptation and host–pathogen interactions. His work is closely aligned with collaborative, data-driven research and the development of reproducible bioinformatics workflows that support both fundamental and translational research.
Pieter Monsieurs obtained a Master’s degree in Bioscience Engineering (Cellular and Genetic Engineering) from KU Leuven in 2002 and a PhD in Bioinformatics in 2006. Prior to joining ITM, he held research positions at SCK-CEN and VITO, where he built broad expertise in computational biology and omics data analysis.
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Collaborations and top research areas from the last five years
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Exploring the non-coding RNA in tsetse fly saliva and its effect on the host innate immune response and trypanosome development at the host skin bite site.
Odhiambo, P. O. (PhD Student), Van Den Abbeele, J. (Promotor), Monsieurs, P. (Promotor), Dujardin, J.-C. (Promotor) & Masiga, D. (Promotor)
1/01/24 → …
Project: PhD-project
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AIM-CL: Antimicrobial adjuvants to revert the Imbalance of skin Microbiota for improved outcomes of Cutaneous Leishmaniasis treatment in Ethiopia
Pareyn, M. (PI), Monsieurs, P. (PI), Van Herrewege, Y. (PI), Van Herrewege, Y. (PI), van Griensven, J. (Promotor), Monsieurs, P. (PI) & Pareyn, M. (PI)
Flemish Government - Department of Work, Economy, Science, Innovation
1/01/23 → 31/12/26
Project: Research Project
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FA5 RD CONGO: Strengthen research and education capacities in the partner institutes (INRB, CRSK, ESP) in DRC (Outcome 1) Support to interruption of transmission of Human African Trypanosomiasis (HAT) by 2030 (Outcome 2)
Verlé, P. (Copromotor), Nicco, E. (Copromotor), Van Cauwenberg, I. (Other), Rosanas-Urgell, A. (Researcher), Mutsaers, M. (Researcher), de Jong, B. (Researcher), Van Den Abbeele, J. (Researcher), Dermauw, V. (Researcher), Ariën, K. (Researcher), Hauner, A. (Researcher), Monsieurs, P. (Researcher), Van Bortel, W. (Researcher), Kreppel, K. (Researcher), Vanlerberghe, V. (Researcher), Ingelbeen, B. (Researcher), Lepore, L. (Researcher), Inocêncio da Luz, R. (Researcher), Semaan, A. (Researcher), Seghers, C.-A. (Researcher), Polman, K. (Researcher), Katsuva, D. (Researcher), Colombe, S. (Researcher), Benova, L. (Copromotor), Meudec, M. (Researcher), Van Den Abbeele, J. (PI), Van Den Abbeele, J. (Promotor) & Kattenberg, E. (Promotor)
Directorate-General for Development Cooperation and Humanitarian Aid
1/01/22 → 31/12/26
Project: Development project
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PvCQR: Mechanisms of P. vivax chloroquine resistance: a transcriptomic/transgenic approach
Kattenberg, E. (Copromotor), Monsieurs, P. (Copromotor), Sauve, E. (Researcher), Rosanas-Urgell, A. (PI) & Rosanas-Urgell, A. (Promotor)
Flemish Government - Department of Work, Economy, Science, Innovation
1/01/21 → 31/12/26
Project: Research Project
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SinCellK: A single-cell approach to study epigenetic regulation of Plasmodium knowlesi phenotypes: red blood cell invasion and gametocyte differentiation processes
Rosanas-Urgell, A. (PI), Monsieurs, P. (Copromotor), De Meulenaere, K. (PhD Student) & Stas, M. (Administrator)
Flemish Government - Department of Economy, Science & Innovation
1/12/21 → 30/11/22
Project: Research Project
Research output
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Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level
Imamura, H., Monsieurs, P., Jara, M., Sanders, M., Maes, I., Vanaerschot, M., Berriman, M., Cotton, J. A., Dujardin, J.-C. & Domagalska, M. A., 2020, In: Scientific Reports. 10, 1, 13 p., 15043.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open AccessFile83 Downloads (Pure) -
PaSiT: a novel approach based on short-oligonucleotide frequencies for efficient bacterial identification and typing
Goussarov, G., Cleenwerck, I., Mysara, M., Leys, N., Monsieurs, P., Tahon, G., Carlier, A., Vandamme, P. & Van Houdt, R., 2020, In: Bioinformatics. 36, 8, p. 2337-2344 8 p.Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review
Open AccessFile37 Downloads (Pure)