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Wim Adriaensen (MSc 2010, double PhD 2015) is an assistant professor and heading the Clinical Immunology Unit in the Department of Clinical Sciences (Institute of Tropical Medicine, Antwerp, Belgium). He was trained in immunology and medical research during his double-PhD in medical sciences and public health (Academic Centre for General Practice, KULeuven and Institute of Health and Society, UCLouvain, Belgium) on the clinical impact of the aging of the immune system and its complex relationship with cytomegalovirus for patient and vaccination outcomes in octogenarians in Belgium; that he performed partly at the University of Tübingen, Germany. He started at ITM as a clinical trial scientist (Clinical Trial Unit, ITM) to gain more affinity with clinical trials and project management on several infectious diseases in low-resource settings. In 2016, he founded a clinical immunology research line within the unit of neglected tropical diseases at ITM with a particular dedication on human cellular immunity and its translation to bench side diagnostic and therapeutic applications, which he still leads to date. After building expertise in visceral leishmaniasis (VL) and establishing a strong network of relevant research, patient and drug development organizations, he acquired a competitive post-doctoral fellowship (Research Foundation Flanders) on the synergistic impact of HIV co-infection on T-cell suppression in VL-HIV patients. Besides establishing single cell and spatial transcriptomic pipelines at ITM, his research is focussed on the development of alternative host-based test-of-cure assays and predictive biomarkers for patient/treatment outcomes. Simulatenously, he strongly invested in capacity building programs in Ethiopia and DRC. In recent years, the research lines were successfully expanded to cutaneous leishmaniasis and recently to rabies and SARS-CoV-2. He has successfully obtained 2,5 million euro as principal investigator from diverse funding sources. He has set-up or assisted in over 15 clinical trials and prospective cohort studies to date.
Msc in Biomedical Sciences
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A framework to deduce the convoluted repertoire and epitope hierarchy of human T cell responses in visceral leishmaniasis: patient meets in silico
3/11/20 → …
20/10/20 → 20/10/21
Project: Research Project
1/09/18 → 30/11/19
Project: Research Project
Leveraging T-cell receptor - epitope recognition models to disentangle unique and cross-reactive T-cell response to SARS-CoV-2 during COVID-19 progression/resolutionPostovskaya, A., Vujkovic, A., de Block, T., van Petersen, L., van Frankenhuijsen, M., Brosius, I., Bottieau, E., Van Dijck, C., Theunissen, C., van Ierssel, S. H., Vlieghe, E., Bartholomeus, E., Mullan, K., Adriaensen, W., Vanham, G., Ogunjimi, B., Laukens, K., Vercauteren, K. & Meysman, P., 2023, In: Frontiers in Immunology. 14, 14 p., 1130876.
Research output: Contribution to journal › A1: Web of Science-article › peer-reviewOpen AccessFile10 Downloads (Pure)
Aetiologies of acute undifferentiated febrile illness at the emergency ward of the University of Gondar Hospital, EthiopiaAkelew, Y., Pareyn, M., Lemma, M., Negash, M., Bewket, G., Derbew, A., Belay, G., Pollmann, J., Adriaensen, W., Peeters, M., Ombelet, S., Adane, A., Mohammed, R., van Griensven, J. & Cnops, L., 2022, In: Tropical Medicine and International Health. 27, 3, p. 271-279 9 p.
Research output: Contribution to journal › A1: Web of Science-article › peer-reviewOpen AccessFile18 Downloads (Pure)
Comparison of serum cytokine levels in symptomatic and asymptomatic HIV-Leishmania coinfected individuals from a Brazilian visceral leishmaniasis endemic areaGuedes, D. L., Silva, E. D. D., Castro, M. C. A. B., Júnior, W. L. B., Ibarra-Meneses, A. V., Tsoumanis, A., Adriaensen, W., van Griensven, J., Pereira, V. R. A. & Medeiros, Z. M. D., 2022, In: PLoS Neglected Tropical Diseases. 16, 6, 12 p., e0010542.
Research output: Contribution to journal › A1: Web of Science-article › peer-reviewOpen AccessFile68 Downloads (Pure)
Adriaensen, W., Owiti, P., Senkoro, M., Zolfo, M. & Nash, S. D., 2022, In: Journal of Infection in Developing Countries. 16, 8.1, p. 8S-14S 7 p.
Research output: Contribution to journal › A1: Web of Science-article › peer-reviewOpen AccessFile17 Downloads (Pure)
Cellular immune phenotypes and worsening scores of frailty-associated parameters over an 18-month period in the very oldGoldeck, D., Adriaensen, W., Oettinger, L., Vaes, B., van Pottelbergh, G., Degryse, J-M., Hamprecht, K., Matheï, C. & Pawelec, G., 2021, In: The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 76, 8, p. 1356-1361 6 p.
Research output: Contribution to journal › A1: Web of Science-article › peer-reviewOpen AccessFile15 Downloads (Pure)