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Wim Adriaensen (MSc 2010, double PhD 2015) is an assistant professor and heading the Clinical Immunology Unit in the Department of Clinical Sciences (Institute of Tropical Medicine, Antwerp, Belgium). He was trained in immunology and medical research during his double-PhD in medical sciences and public health (Academic Centre for General Practice, KULeuven and Institute of Health and Society, UCLouvain, Belgium) on the clinical impact of the aging of the immune system and its complex relationship with cytomegalovirus for patient and vaccination outcomes in octogenarians in Belgium; that he performed partly at the University of Tübingen, Germany. He started at ITM as a clinical trial scientist (Clinical Trial Unit, ITM) to gain more affinity with clinical trials and project management on several infectious diseases in low-resource settings. In 2016, he founded a clinical immunology research line within the unit of neglected tropical diseases at ITM with a particular dedication on human cellular immunity and its translation to bench side diagnostic and therapeutic applications, which he still leads to date. After building expertise in visceral leishmaniasis (VL) and establishing a strong network of relevant research, patient and drug development organizations, he acquired a competitive post-doctoral fellowship (Research Foundation Flanders) on the synergistic impact of HIV co-infection on T-cell suppression in VL-HIV patients. Besides establishing single cell and spatial transcriptomic pipelines at ITM, his research is focussed on the development of alternative host-based test-of-cure assays and predictive biomarkers for patient/treatment outcomes. Simulatenously, he strongly invested in capacity building programs in Ethiopia and DRC. In recent years, the research lines were successfully expanded to cutaneous leishmaniasis and recently to rabies and SARS-CoV-2. He has successfully obtained 2,5 million euro as principal investigator from diverse funding sources. He has set-up or assisted in over 15 clinical trials and prospective cohort studies to date.
Msc in Biomedical Sciences
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SpatialCL: Spacial analysis of host-parasite interactions in the skin across the clinical spectrum of cutaneous leishmaniasis in Ethiopia
1/01/21 → 31/12/23
Project: Research Project
A framework to deduce the convoluted repertoire and epitope hierarchy of human T cell responses in visceral leishmaniasis: patient meets in silico
3/11/20 → …
Etiologies of acute undifferentiated febrile illness at the emergency ward of the University of Gondar Hospital, EthiopiaAkelew, Y., Pareyn, M., Lemma, M., Negash, M., Bewket, G., Derbew, A., Belay, G., Pollmann, J., Adriaensen, W., Peeters, M., Ombelet, S., Adane, A., Mohammed, R., van Griensven, J. & Cnops, L., 2022, In : Tropical Medicine and International Health.
Research output: Contribution to journal › A1: Web of Science-article
HLA-DRB1 alleles associated with lower leishmaniasis susceptibility share common amino acid polymorphisms and epitope binding repertoiresde Vrij, N., Meysman, P., Gielis, S., Adriaensen, W., Laukens, K. & Cuypers, B., 2021, In : Vaccines. 9, 3, 17 p., 270.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile2 Downloads (Pure)
Diagnostic accuracy of direct agglutination test, rK39 ELISA and six rapid diagnostic tests among visceral leishmaniasis patients with and without HIV coinfection in EthiopiaKassa, M., Abdellati, S., Cnops, L., Bremer Hinckel, B. C., Yeshanew, A., Hailemichael, W., Vogt, F., Adriaensen, W., Mertens, P., Diro, E., van Griensven, J. & Van den Bossche, D., 2020, In : PLoS Neglected Tropical Diseases. 14, 12, 13 p., e0008963.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile8 Downloads (Pure)
Evaluation of C-reactive protein and myxovirus resistance protein A to guide the rational use of antibiotics among acute febrile adult patients in Northwest EthiopiaAkelew, Y., Derbew, A., Lemma, M., Negash, M., Bewket, G., Belay, G., Pollmann, J., Adriaensen, W., Adane, A., Mohammed, R., van Griensven, J. & Cnops, L., 2020, In : International Journal of Infectious Diseases. 101, p. 276-282 7 p.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile15 Downloads (Pure)
Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIVAdriaensen, W., Cuypers, B., Cordero, C. F., Mengasha, B., Blesson, S., Cnops, L., Kaye, P. M., Alves, F., Diro, E. & van Griensven, J., 2020, In : EBioMedicine. 55, 12 p., 102748.
Research output: Contribution to journal › A1: Web of Science-articleOpen AccessFile4 Downloads (Pure)