Projects per year
Personal profile
Research expertise
Wim Adriaensen (MSc 2010, double PhD 2015) is an associate professor and heading the Clinical Immunology Unit in the Department of Clinical Sciences (Institute of Tropical Medicine, Antwerp, Belgium). He was trained in immunology and medical research during his double-PhD in medical sciences and public health (Academic Centre for General Practice, KULeuven and Institute of Health and Society, UCLouvain, Belgium) on the clinical impact of the aging of the immune system and its complex relationship with cytomegalovirus for patient and vaccination outcomes in octogenarians in Belgium; that he performed partly at the University of Tübingen, Germany. He started at ITM as a clinical trial scientist (Clinical Trial Unit, ITM) to gain more affinity with clinical trials and project management on several infectious diseases in low-resource settings. In 2016, he founded a clinical immunology research line within the unit of neglected tropical diseases at ITM with a particular dedication on human cellular immunity and its translation to bench side diagnostic and therapeutic applications, which he still leads to date. After building expertise in visceral leishmaniasis (VL) and establishing a strong network of relevant research, patient and drug development organizations, he acquired a competitive post-doctoral fellowship (Research Foundation Flanders) on the synergistic impact of HIV co-infection on T-cell suppression in VL-HIV patients. Besides establishing single cell and spatial transcriptomic pipelines at ITM, his research is focussed on the development of alternative host-based test-of-cure assays and predictive biomarkers for patient/treatment outcomes. Simulatenously, he strongly invested in capacity building programs in Ethiopia and DRC. In recent years, the research lines were successfully expanded to cutaneous leishmaniasis and recently to rabies and SARS-CoV-2. He has successfully obtained 2,5 million euro as principal investigator from diverse funding sources. He has set-up or assisted in over 15 clinical trials and prospective cohort studies to date.
Education/Academic qualification
Msc in Biomedical Sciences
Master
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Projects
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A framework to deduce the convoluted repertoire and epitope hierarchy of human T cell responses in visceral leishmaniasis: patient meets in silico
De Vrij, N., van Griensven, J., Adriaensen, W., Laukens, K., Cuypers, B. & Cuypers, B.
3/11/20 → …
Project: PhD-project
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Persistent T-cell dysfunction in synergistic VL-HIV co-infection
Adriaensen, W., van Griensven, J., Vermeesch, J. R., Kaye, P. M., Diro, E., Ritmeijer, K. & Ratsarahery, L.
Fonds voor Wetenschappelijk Onderzoek
1/10/17 → 30/09/20
Project: Research Project
Research output
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Diagnostic accuracy of direct agglutination test, rK39 ELISA and six rapid diagnostic tests among visceral leishmaniasis patients with and without HIV coinfection in Ethiopia
Kassa, M., Abdellati, S., Cnops, L., Bremer Hinckel, B. C., Yeshanew, A., Hailemichael, W., Vogt, F., Adriaensen, W., Mertens, P., Diro, E., van Griensven, J. & Van den Bossche, D., 2020, In : PLoS Neglected Tropical Diseases. 14, 12, p. e0008963Research output: Contribution to journal › A1: Web of Science-article
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Host transcriptomic signature as alternative test-of-cure in visceral leishmaniasis patients co-infected with HIV
Adriaensen, W., Cuypers, B., Cordero, C. F., Mengasha, B., Blesson, S., Cnops, L., Kaye, P. M., Alves, F., Diro, E. & van Griensven, J., 2020, In : EBioMedicine. 55, p. 102748Research output: Contribution to journal › A1: Web of Science-article
Open AccessFile1 Downloads (Pure) -
Minimally invasive microbiopsies as an improved sampling method for the diagnosis of cutaneous leishmaniasis
Churiso, G., van Henten, S., Cnops, L., Pollmann, J., Melkamu, R., Lemma, M., Kiflie, A., Fikre, H., van Griensven, J. & Adriaensen, W., 2020, In : Open Forum Infectious Diseases. 7, 9, p. ofaa364Research output: Contribution to journal › A1: Web of Science-article
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Sexual transmission of visceral leishmaniasis: a neglected story
Guedes, D. L., van Henten, S., Cnops, L., Adriaensen, W. & van Griensven, J., 2020, In : Trends In Parasitology. 36, 12, p. 950-952 3 p.Research output: Contribution to journal › A1: Web of Science-article
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Towards the trachoma elimination target in the southern region of Ethiopia: how well is the SAFE strategy being implemented?
Asfaw, M., Zolfo, M., Negussu, N., Tadesse, F., Tadele, T., Sisay, A., Seyum, D., Gezmu, T., Senkoro, M., Owiti, P. & Adriaensen, W., 2020, In : Journal of Infection in Developing Countries. 14, 6.1, p. 3S-9S 7 p.Research output: Contribution to journal › A1: Web of Science-article
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