CORNERSTONE - Containment of Antimicrobial resistance: towards a sustainable poultry production chain in Indonesia

Project Details


The increasing level of antimicrobial resistant (AMR) pathogens (particularly bacteria) that cause disease in animals and humans is one of the major (public) health concerns worldwide. Without taking action, AMR is estimated to become one of the greatest human mortalities by 2050, alongside monetary costs of $1 billion1,2. Recognition of the magnitude of the global AMR problem by the World Health Organization (WHO), the Food and Agriculture Organization of the United Nations (FAO), and the World Organization for Animal Health (OIE), has led the Heads of States to adopt a resolution of containment during the United Nations General Assembly (UNGA) in September 20163.

There is a strong correlation between antimicrobial use (AMU) and AMR4. Therefore, it is important that the prudent use of antimicrobials is promoted in both humans and animals. The AMR challenges faced by Indonesia are similar to those of many other low and middle-income countries across Asia. Due to easy (over the counter) availability of antimicrobials, there is extensive misuse and overuse of antimicrobials in human medicine, in livestock production and aquaculture; antimicrobials are believed to be widely used in a preventive manner by farmers as insurance against animal diseases and to compensate for poor management that increases disease risks in animals. These applications of antimicrobials form the key drivers of resistance in livestock and humans are exposed to resistant bacteria through the food chain. With rapid growth of the Indonesian economy over the past decade, the level of consumption and production of poultry meat and eggs has increased concurrently and is estimated to consist of 87% of the total meat consumption5.This has also impacted on the use of antimicrobials in poultry and has increased AMR-related risks in both the poultry sector and in terms of human health. A rough estimate is that currently antimicrobial consumption in typical Indonesian broiler farms is about 10 times higher compared to broiler farms in the Netherlands. Although comparisons between countries are difficult to make, this shows that AMU in Indonesian broiler production is huge. For sustainable and efficient production of animal derived food products (eggs, meat) in the future, with limited AMR risks for animals and humans, Indonesian farmers need to shift to alternative practices to largely replace the use of antimicrobials. Alternatives to using antimicrobials can be the implementation of better on-farm biosecurity (a set of management measures designed to reduce the risk of introduction and spread of animal diseases) and hygiene other housing systems, improved vaccination regimes and others. There is however a lack of data on how much and which antimicrobials are being used and the reasons why they are applied. Additionally, there is a lack of evidence on which alternatives to antimicrobials are feasible, affordable and (cost) effective in Indonesian poultry systems.

This research project will strive to provide accurate and usable data regarding AMU and AMR in the Indonesian poultry sector. Through extensive and thorough collection of data, evidence could be collected on feasible and affordable alternatives for antimicrobial products, contributing to a sustainable poultry production chain in Indonesia. The unique collaboration within this project will ensure that the project results will be disseminated to both policy level and practice level and thereby will potentially have a huge impact on nationwide AMU in broiler production. Additionally, Indonesia is seen by many countries in the region as a showcase for AMU policy and many consortium members from the CORNERSTONE project are very active in the Asia region working on AMU in food producing animals.

Effective interventions will therefore not only impact broiler production in Indonesia, but also in the wider region.
Effective start/end date16/11/23 → …