Project Details
Description
We are still struggling to control a 17-year old outbreak of syphilis in Belgium. Most cases occur in HIV-infected individuals and increasingly involve reinfections. Current diagnostic tests are performing poorly in these circumstances. As a result, we are trying to develop a new diagnostic test that could directly detect Treponema pallidum proteins in the blood, urine and cerebrospinal fluid of patients with syphilis. This would be a boon to patient management and the control of syphilis. Our project has uncovered 6 promising protein candidates for such a test in the urine of patients with syphilis. In this proposal, we would like to apply for an extra sum of €60 762 to cover the cost of producing monoclonal antibodies that will be used in the construction of a diagnostic assay via the “Stable isotope standards and capture by anti-peptide antibodies (SISCAPA)” technique.
Acronym | SeTPAT |
---|---|
Status | Finished |
Effective start/end date | 1/01/18 → 30/11/20 |
Funding
- King Baudouin Foundation: €50,000.00
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