European Cooperation for anti-Viral Drug discovery and preparedness for current and emerging coronavirus outbreaks

Project Details

Description

In just two months, the SARS-CoV2 outbreak has become a global pandemic that killed almost 30K people and infected more than 600K man and women worldwide, imposing an unprecedented lockdown on world-wide scale, with huge socioeconomic consequences. Health-care professionals are currently in the frontline of this “war”, saving lives, protecting the medically fragile population, while governments are trying to contain the spreading of SARS-CoV2 through severe and costly lock-down measures. All these efforts have the ultimate scope of buying time to the scientific community to rapidly identify a
specific SARS-Cov2 antiviral. The EUROCOVID consortium is ready to accept this challenge and has brought together a well-integrated network of (public/private) EU experts in antiviral drug-discovery for the development of pan-coronavirus
antivirals that will rapidly respond to the current SARS-CoV2 outbreak and to future related outbreaks or mutations leading to drug-resistance. To leave no stone unturned, EUROCOVID will pursue two different objectives at the same time: 1) a rationale fast-track drug repurposing to identify in 1.5 years’ timeframe a drug to be progressed in Phase IIa/IIb studies; 2) a wide drug discovery effort to discover new broad-spectrum antivirals (preclinical candidates) as a preparedness measures to offer the possibility of immediately initiating prophylactic (in the absence of an effective vaccine) as well as a therapeutic treatment for the current outbreak or in case of future viral outbreaks of unknown aetiology or the development of drugresistance
mutations. These two objectives well describe the EUROCOVID mission of mitigating the Coronavirus threat and our vision towards the development of “penicillin-like” antivirals.
AcronymREMCoV
StatusFinished
Effective start/end date1/04/2028/02/21

Funding

  • Flemish Government - Department of Economy, Science & Innovation: €25,000.00

Flemish disciplinelist

  • Virology
  • Infectious diseases