Project Details
Description
General
The effective inhibition of HIV replication targeting viral escape and resistance under immune and drug pressure.
Specific
In silico: to genotype HIV drug resistance interpretation and predict HIV evolution with applied and optimalized resistance algorithms and fitness models as bio-informatics tools.In vitro: to study new therapeutic HIV targets, siRNA manipulation and gene therapy, and the induction of anti-HIV cellular immune responses using normal donor and patients' blood cells and viral strains.In vivo: to test the experimental immunological in vitro findings on relevance and/or efficiency in a Trimera mouse HIV model.
| Acronym | HIV Control |
|---|---|
| Status | Finished |
| Effective start/end date | 1/01/07 → 31/03/12 |