The long-term objective is to improve effectiveness of control programmes (i.e drug treatment and putative anti-schistosome vaccines), or alternatively, to promote immunoregulatory networks in individuals with severe morbidity.
To define innate immune responses in patients infected with schistosomes that are associated with down-regulation of acquired immune responses, or conversely the development of pathology.To characterise and manufacture parasite-derived immunoregulatory molecules.To use parasite-derived molecules to manipulate protective immune responses and immunopathology.To aid existing control programmes by using epidemiological and geographic data gathered in the field.
|Effective start/end date
|1/11/06 → 31/10/10
- European Commission: €249,000.00
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