Abstract
Sexually transmitted Chlamydia trachomatis infections remain common globally and most frequently are asymptomatic. The 2025 European C. trachomatis guideline provides up-to-date guidance regarding indications for testing and treatment of C. trachomatis infections. It includes advice on urogenital and extragenital C. trachomatis testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all C. trachomatis infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for C. trachomatis infections is also discussed.
| Original language | English |
|---|---|
| Journal | International Journal of STD & AIDS |
| Volume | 36 |
| Issue number | 6 |
| Pages (from-to) | 434-449 |
| Number of pages | 16 |
| ISSN | 0956-4624 |
| DOIs | |
| Publication status | Published - May-2025 |
Keywords
- <italic>Chlamydia trachomatis</italic>
- Europe
- Antibiotic
- Diagnosis
- Treatment
- Doxycycline/therapeutic use
- Chlamydia trachomatis/isolation & purification
- Humans
- Chlamydia Infections/drug therapy
- Mass Screening
- Azithromycin/therapeutic use
- Anti-Bacterial Agents/therapeutic use
- Practice Guidelines as Topic
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