A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

Francesca Falconi-Agapito; Philippe Selhorst; Xiomara Merino; Fiorella Torres; Johan Michiels; Connie Fernandez; Michael Talledo; Kevin K Ariën

doi:10.1016/j.ijid.2020.04.087

A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

Francesca Falconi-Agapito
, Philippe Selhorst
, Xiomara Merino
, Fiorella Torres
, Johan Michiels
, Connie Fernandez
, Michael Talledo
, Kevin K Ariën

Virology

Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review

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Abstract

We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

Original language	English
Journal	International Journal of Infectious Diseases
Volume	96
Pages (from-to)	136-138
Number of pages	3
ISSN	1201-9712
DOIs	https://doi.org/10.1016/j.ijid.2020.04.087
Publication status	Published - 2020

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10.1016/j.ijid.2020.04.087Licence: CC BY-NC-ND

2020ijid0136Final published version, 1,000 KBLicence: CC BY-NC-ND

PERU - FA4: To strengthen the R&D capacities of the Institute of Tropical Medicine Alexander von Humboldt (Peru) to deliver strategies and/or tools for diagnosis, surveillance and control of infectious diseases.
Dujardin, J.-C. (Promotor), Van der Auwera, G. (Coordinator), Rosanas-Urgell, A. (Researcher), de Jong, B. (Researcher), Ariën, K. (Researcher), Rigouts, L. (Researcher), Heyndrickx, L. (Researcher), Kattenberg, E. (Researcher), Battaglioli, T. C. E. (Researcher), Jacobs, J. (Researcher), Monsieurs, P. (Researcher), Guetens, P. (Researcher) & Müller, R. (Researcher)
Directorate-General for Development Cooperation and Humanitarian Aid
1/11/17 → 31/12/21
Project: Development project

Cite this

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title = "A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon",

abstract = "We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.",

author = "Francesca Falconi-Agapito and Philippe Selhorst and Xiomara Merino and Fiorella Torres and Johan Michiels and Connie Fernandez and Michael Talledo and Ari{\"e}n, \{Kevin K\}",

year = "2020",

doi = "10.1016/j.ijid.2020.04.087",

language = "English",

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pages = "136--138",

journal = "International Journal of Infectious Diseases",

issn = "1201-9712",

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T1 - A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

AU - Falconi-Agapito, Francesca

AU - Selhorst, Philippe

AU - Merino, Xiomara

AU - Torres, Fiorella

AU - Michiels, Johan

AU - Fernandez, Connie

AU - Talledo, Michael

AU - Ariën, Kevin K

PY - 2020

Y1 - 2020

N2 - We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

AB - We sequenced the envelope gene of dengue virus serotype 2 (DENV-2-E) in samples from an outbreak reported in 2018, in Yurimaguas, Peru. The strain belongs to lineage 2 of the American/Asian genotype. We report a variant with two novel mutations (I379T and V484I) located in domain III of DENV2-E.

U2 - 10.1016/j.ijid.2020.04.087

DO - 10.1016/j.ijid.2020.04.087

M3 - A1: Peer-reviewed journal articles

C2 - 32387448

SN - 1201-9712

VL - 96

SP - 136

EP - 138

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

ER -

A new genetic variant of dengue serotype 2 virus circulating in the Peruvian Amazon

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PERU - FA4: To strengthen the R&D capacities of the Institute of Tropical Medicine Alexander von Humboldt (Peru) to deliver strategies and/or tools for diagnosis, surveillance and control of infectious diseases.

Cite this