A "One Health" surveillance and control of brucellosis in developing countries: moving away from improvisation

J. Godfroid, S. Al Dahouk, G. Pappas, F. Roth, G. Matope, J. Muma, T. Marcotty, D. Pfeiffer, E. Skjerve

    Research output: Contribution to journalA1: Web of Science-articlepeer-review

    17 Downloads (Pure)

    Abstract

    Although a "One Health" approach has been successfully implemented for emerging infectious zoonotic diseases with pandemic potential, we still lack a conceptual framework to address enzootic diseases like brucellosis. The vast majority of published brucellosis studies in the developing world rely solely on serology. An important shortcoming of brucellosis serology is the impossibility to infer which (smooth) Brucella spp. induced antibodies in the host. In this respect, mixed farming and especially raising small ruminants along with cattle, a common practice in the developing world, is reported to be a risk factor and a central question that has to be answered is whether cattle are infected with B. melitensis or with B. abortus or with both Brucella species. Therefore the isolation, identification and molecular characterization of Brucella spp. in human and the different livestock species needs to be undertaken to define a sound conceptual framework, identify the source of infection and plan appropriate control measures.
    Original languageEnglish
    JournalComparative Immunology, Microbiology and Infectious Diseases
    Volume36
    Issue number3
    Pages (from-to)241-248
    Number of pages8
    ISSN0147-9571
    DOIs
    Publication statusPublished - 2013

    Keywords

    • Bacterial diseases
    • Zoonoses
    • Brucellosis
    • Brucella
    • Control strategies
    • Integrated control
    • Surveillance
    • Framework
    • Serology
    • Isolation
    • Identification
    • Molecular
    • Characterization
    • Mass campaigns
    • Vaccinations
    • Herds
    • Wildlife
    • Developing countries

    Fingerprint

    Dive into the research topics of 'A "One Health" surveillance and control of brucellosis in developing countries: moving away from improvisation'. Together they form a unique fingerprint.

    Cite this