Аn antibody detection ELISA for diagnosis of Т.Ь. gambiense infection in man is presented. Тhe antigens consist of semi-purified variable surface glycoprotein of two different antigen types (VATs) of Т.Ь. gambiense. Both antigens were tested separately and as а mixture. А first evaluation of this ELISA оп 351 human Т.Ь. gambiense infection sera and 635 поп trypanosomiasis sera revealed high sensitivity and specificity. Тhe necessity of using а combination of VATs is demonstrated Ьу the rеlаtiопslliр between the geographical origin of the serum samples and the sensitivity of thee single antigen tests.
|Title of host publication||International Scientific Council for Trypanosomiasis Research and Control (ISCTRC); twenty second meeting, Kampala, Uganda, 1993|
|Place of Publication||Nairobi|
|Publisher||Organization of African Unity, Scientific and Technical Research Council (OAU/STRC)|
|Publication status||Published - 1995|
- Trypanosoma brucei gambiense