A virus becomes a global concern: research activities on West-Nile virus

D Klingelhöfer, M Braun, IM Kramer, F Reuss, R Müller, DA Groneberg, D Brueggmann

Research output: Contribution to journalA1: Web of Science-articlepeer-review


Currently, West-Nile virus (WNV) is spreading worldwide to colder regions due to climate change. Human mortality and morbidity are prevalent and steadily increasing, associated with costs to public health systems. Therefore, the question of the impact of scientific engagement arises. What trends, barriers, and incentives for research related to global burdens are important in this context? To answer these questions, this study provides detailed insights into the publication patterns of WNV research and interprets them using several parameters, such as absolute and relative publication indices and socioeconomic and epidemiological characteristics. It is shown that national interests combined with regional outbreaks significantly influence publication intensity. Thus, a correlation between national publication volume and the number of WNV cases was observed. In contrast to most life science topics, the scientific interest in WNV significantly decreased after 2006. The USA, as the main actor in WNV research, is at the centre of international networking. Recently, European countries are also getting involved according to their new-emerging outbreaks. The results demonstrate national interest in research activities with a lack of globally focused approaches that are urgently needed to better understand and assess the distribution and characteristics of WNV.
Original languageEnglish
Article number2256424
JournalEmerging Microbes & Infections
Number of pages12
Publication statusPublished - 2023


  • Culex
  • Emerging pathogens
  • Infectious diseases
  • Mosquitos
  • Vector-borne diseases


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