Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms

KWA van Grinsven; J Van Den Abbeele; P Van den Bossche; JJ van Hellemond; AGM Tielens

doi:10.1128/EC.00091-09

Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms

KWA van Grinsven
, J Van Den Abbeele
, P Van den Bossche
, JJ van Hellemond
, AGM Tielens

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

Original language	English
Journal	Eukaryotic Cell
Volume	8
Issue number	8
Pages (from-to)	1307-1311
Number of pages	5
ISSN	1535-9778
DOIs	https://doi.org/10.1128/EC.00091-09
Publication status	Published - 2009

Keywords

B780-tropical-medicine
Protozoology
Trypanosoma brucei
Glucose metabolism
Mitochondria
Adaptation

Access to Document

10.1128/EC.00091-09

Cite this

@article{b46591174d414dcfa09e4332eda6cc40,

title = "Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms",

abstract = "Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.",

keywords = "B780-tropical-medicine, Protozoology, Trypanosoma brucei, Glucose metabolism, Mitochondria, Adaptation",

author = "\{van Grinsven\}, KWA and \{Van Den Abbeele\}, J and \{Van den Bossche\}, P and \{van Hellemond\}, JJ and AGM Tielens",

note = "FTX abonnement",

year = "2009",

doi = "10.1128/EC.00091-09",

language = "English",

volume = "8",

pages = "1307--1311",

journal = "Eukaryotic Cell",

issn = "1535-9778",

publisher = "American Society for Microbiology",

number = "8",

}

TY - JOUR

T1 - Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms

AU - van Grinsven, KWA

AU - Van Den Abbeele, J

AU - Van den Bossche, P

AU - van Hellemond, JJ

AU - Tielens, AGM

N1 - FTX abonnement

PY - 2009

Y1 - 2009

N2 - Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

AB - Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

KW - B780-tropical-medicine

KW - Protozoology

KW - Trypanosoma brucei

KW - Glucose metabolism

KW - Mitochondria

KW - Adaptation

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000268760500020

U2 - 10.1128/EC.00091-09

DO - 10.1128/EC.00091-09

M3 - A1: Web of Science-article

SN - 1535-9778

VL - 8

SP - 1307

EP - 1311

JO - Eukaryotic Cell

JF - Eukaryotic Cell

IS - 8

ER -

Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this