An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses

M. Singh; P. Singh; G. Gaudray; L. Musumeci; C. Thielen; D. Vaira; C. Vandergeeten; L. Delacroix; E. Van Gulck; G. Vanham; L. de Leval; S. Rahmouni; M. Moutschen

doi:10.1371/journal.pone.0038491

An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses

M. Singh
, P. Singh
, G. Gaudray
, L. Musumeci
, C. Thielen
, D. Vaira
, C. Vandergeeten
, L. Delacroix
, E. Van Gulck
, G. Vanham
, L. de Leval
, S. Rahmouni
, M. Moutschen

Virology

Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review

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Original language	English
Journal	PLoS ONE
Volume	7
Issue number	6
Pages (from-to)	e38491
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0038491
Publication status	Published - 2012

Keywords

Viral diseases
HIV
AIDS
Immune response
Replication
Protocols
In vivo
Mice
Transplantation
Irradiation
T-cells
CD34+
CD3
Cell count
Immune activation
Inflammation
Translocation
Laboratory techniques and procedures

Access to Document

10.1371/journal.pone.0038491

2012ponee38491Final published version, 1.31 MB

Cite this

Singh, M., Singh, P., Gaudray, G., Musumeci, L., Thielen, C., Vaira, D., Vandergeeten, C., Delacroix, L., Van Gulck, E., Vanham, G., de Leval, L., Rahmouni, S., & Moutschen, M. (2012). An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses. PLoS ONE, 7(6), e38491. https://doi.org/10.1371/journal.pone.0038491

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keywords = "Viral diseases, HIV, AIDS, Immune response, Replication, Protocols, In vivo, Mice, Transplantation, Irradiation, T-cells, CD34+, CD3, Cell count, Immune activation, Inflammation, Translocation, Laboratory techniques and procedures",

author = "M. Singh and P. Singh and G. Gaudray and L. Musumeci and C. Thielen and D. Vaira and C. Vandergeeten and L. Delacroix and \{Van Gulck\}, E. and G. Vanham and \{de Leval\}, L. and S. Rahmouni and M. Moutschen",

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Singh, M, Singh, P, Gaudray, G, Musumeci, L, Thielen, C, Vaira, D, Vandergeeten, C, Delacroix, L, Van Gulck, E, Vanham, G, de Leval, L, Rahmouni, S & Moutschen, M 2012, 'An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses', PLoS ONE, vol. 7, no. 6, pp. e38491. https://doi.org/10.1371/journal.pone.0038491

TY - JOUR

T1 - An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses

AU - Singh, M.

AU - Singh, P.

AU - Gaudray, G.

AU - Musumeci, L.

AU - Thielen, C.

AU - Vaira, D.

AU - Vandergeeten, C.

AU - Delacroix, L.

AU - Van Gulck, E.

AU - Vanham, G.

AU - de Leval, L.

AU - Rahmouni, S.

AU - Moutschen, M.

N1 - ITG-B9B; ITG-B10A; DBM; U-VIROL; JIF; E-only; DOI; PDF; DSPACE

PY - 2012

Y1 - 2012

KW - Viral diseases

KW - HIV

KW - AIDS

KW - Immune response

KW - Replication

KW - Protocols

KW - In vivo

KW - Mice

KW - Transplantation

KW - Irradiation

KW - T-cells

KW - CD34+

KW - CD3

KW - Cell count

KW - Immune activation

KW - Inflammation

KW - Translocation

KW - Laboratory techniques and procedures

U2 - 10.1371/journal.pone.0038491

DO - 10.1371/journal.pone.0038491

M3 - A1: Peer-reviewed journal articles

C2 - 22675567

SN - 1932-6203

VL - 7

SP - e38491

JO - PLoS ONE

JF - PLoS ONE

IS - 6

ER -