Antimicrobial resistance and COVID-19: intersections and implications

Gwenan M. Knight, Rebecca E. Glover, C. Finn McQuaid, Ioana D. Olaru, Karin Gallandat, Quentin J. Leclerc, Naomi M. Fuller, Sam J. Willcocks, Rumina Hasan, Esther van Kleef, Clare I. R. Chandler

    Research output: Contribution to journalA1: Web of Science-article

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    Abstract

    Before the coronavirus 2019 (COVID-19) pandemic began, antimicrobial resistance (AMR) was among the top priorities for global public health. Already a complex challenge, AMR now needs to be addressed in a changing healthcare landscape. Here, we analyse how changes due to COVID-19 in terms of antimicrobial usage, infection prevention, and health systems affect the emergence, transmission, and burden of AMR. Increased hand hygiene, decreased international travel, and decreased elective hospital procedures may reduce AMR pathogen selection and spread in the short term. However, the opposite effects may be seen if antibiotics are more widely used as standard healthcare pathways break down. Over 6 months into the COVID-19 pandemic, the dynamics of AMR remain uncertain. We call for the AMR community to keep a global perspective while designing finely tuned surveillance and research to continue to improve our preparedness and response to these intersecting public health challenges.

    Original languageEnglish
    Article number64139
    JournaleLIFE
    Volume10
    Number of pages27
    ISSN2050-084X
    DOIs
    Publication statusPublished - 2021

    Keywords

    • Anti-Bacterial Agents/supply & distribution
    • COVID-19/drug therapy
    • Communicable Disease Control/methods
    • Critical Pathways/organization & administration
    • Drug Resistance, Bacterial/physiology
    • Global Health/trends
    • Humans
    • SARS-CoV-2

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