Application of coulometric electrode array detection to the analysis of isoflavonoids and lignans

Jose L. Penalvo, Tarja Nurmi

Research output: Contribution to journalReviewpeer-review

Abstract

A comprehensive review of the available methods for the analysis of isoflavonoids and lignans in biological matrices based on coulometric electrode array detection (CEAD) is presented. Different aspects such as sample extraction and purification procedures as well as instrumental settings and method validation are discussed. Comparisons with other available protocols using different detection techniques such as mass spectrometry or immunoassay are also reported to underline the versatility and reliability of the detector. Practical notes and tips for scientists working with CEAD are also provided. (c) 2006 Elsevier B.V. All rights reserved.

Original languageEnglish
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume41
Issue number5
Pages (from-to)1497-1507
Number of pages11
ISSN0731-7085
DOIs
Publication statusPublished - 28-Aug-2006

Keywords

  • coularray
  • coulometric
  • isoflavonoids
  • lignans
  • phytoestrogens
  • PERFORMANCE LIQUID-CHROMATOGRAPHY
  • MASS-SPECTROMETRIC METHOD
  • TIME-RESOLVED FLUOROIMMUNOASSAY
  • PLANT LIGNANS
  • HUMAN PLASMA
  • HUMAN URINE
  • INTESTINAL METABOLISM
  • SERUM ENTEROLACTONE
  • MAMMALIAN LIGNANS
  • RED-CLOVER

Cite this