Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

F.E. Graf; P. Ludin; T. Wenzler; M. Kaiser; R. Brun; P.P. Pyana; P. Büscher; H.P. de Koning; D. Horn; P. Mäser

doi:10.1371/journal.pntd.0002475

Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

F.E. Graf, P. Ludin, T. Wenzler, M. Kaiser, R. Brun, P.P. Pyana, P. Büscher, H.P. de Koning, D. Horn, P. Mäser

Research output: Contribution to journal › A1: Web of Science-article › peer-review

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Original language	English
Journal	PLoS Neglected Tropical Diseases
Volume	7
Issue number	10
Pages (from-to)	e2475
ISSN	1935-2727
DOIs	https://doi.org/10.1371/journal.pntd.0002475
Publication status	Published - 2013

Keywords

Protozoal diseases
Sleeping sickness
Trypanosomiasis-African
Trypanosoma brucei gambiense
Trypanosoma brucei rhodesiense
Vectors
Tsetse flies
Glossina morsitans
Drug susceptibility
Drug resistance
Pentamidine
Melarsoprol
Sensitivity
Phenotyping
Genotyping
Strains
Isolation
Mutations
In vitro
Cultivation
Africa-General

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10.1371/journal.pntd.0002475

2013pntde2475Final published version, 318 KB

Cite this

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title = "Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol",

keywords = "Protozoal diseases, Sleeping sickness, Trypanosomiasis-African, Trypanosoma brucei gambiense, Trypanosoma brucei rhodesiense, Vectors, Tsetse flies, Glossina morsitans, Drug susceptibility, Drug resistance, Pentamidine, Melarsoprol, Sensitivity, Phenotyping, Genotyping, Strains, Isolation, Mutations, In vitro, Cultivation, Africa-General",

author = "F.E. Graf and P. Ludin and T. Wenzler and M. Kaiser and R. Brun and P.P. Pyana and P. B{\"u}scher and {de Koning}, H.P. and D. Horn and P. M{\"a}ser",

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TY - JOUR

T1 - Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

AU - Graf, F.E.

AU - Ludin, P.

AU - Wenzler, T.

AU - Kaiser, M.

AU - Brun, R.

AU - Pyana, P.P.

AU - Büscher, P.

AU - de Koning, H.P.

AU - Horn, D.

AU - Mäser, P.

N1 - ITG-B6B; ITG-B7A; DBM; U-PARDIA; JIF; DOI; PDF; E-only; DSPACE56 FTX

PY - 2013

Y1 - 2013

KW - Protozoal diseases

KW - Sleeping sickness

KW - Trypanosomiasis-African

KW - Trypanosoma brucei gambiense

KW - Trypanosoma brucei rhodesiense

KW - Vectors

KW - Tsetse flies

KW - Glossina morsitans

KW - Drug susceptibility

KW - Drug resistance

KW - Pentamidine

KW - Melarsoprol

KW - Sensitivity

KW - Phenotyping

KW - Genotyping

KW - Strains

KW - Isolation

KW - Mutations

KW - In vitro

KW - Cultivation

KW - Africa-General

U2 - 10.1371/journal.pntd.0002475

DO - 10.1371/journal.pntd.0002475

M3 - A1: Web of Science-article

SN - 1935-2727

VL - 7

SP - e2475

JO - PLoS Neglected Tropical Diseases

JF - PLoS Neglected Tropical Diseases

IS - 10

ER -