Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

F.E. Graf; P. Ludin; T. Wenzler; M. Kaiser; R. Brun; P.P. Pyana; P. Büscher; H.P. de Koning; D. Horn; P. Mäser

doi:10.1371/journal.pntd.0002475

Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

F.E. Graf
, P. Ludin
, T. Wenzler
, M. Kaiser
, R. Brun
, P.P. Pyana
, P. Büscher
, H.P. de Koning
, D. Horn
, P. Mäser

Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review

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Original language	English
Journal	PLoS Neglected Tropical Diseases
Volume	7
Issue number	10
Pages (from-to)	e2475
ISSN	1935-2727
DOIs	https://doi.org/10.1371/journal.pntd.0002475
Publication status	Published - 2013

Keywords

Protozoal diseases
Sleeping sickness
Trypanosomiasis-African
Trypanosoma brucei gambiense
Trypanosoma brucei rhodesiense
Vectors
Tsetse flies
Glossina morsitans
Drug susceptibility
Drug resistance
Pentamidine
Melarsoprol
Sensitivity
Phenotyping
Genotyping
Strains
Isolation
Mutations
In vitro
Cultivation
Africa-General

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10.1371/journal.pntd.0002475

2013pntde2475Final published version, 318 KB

Cite this

@article{1f66f7772b6a40f99ea477cfa92c3288,

title = "Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol",

keywords = "Protozoal diseases, Sleeping sickness, Trypanosomiasis-African, Trypanosoma brucei gambiense, Trypanosoma brucei rhodesiense, Vectors, Tsetse flies, Glossina morsitans, Drug susceptibility, Drug resistance, Pentamidine, Melarsoprol, Sensitivity, Phenotyping, Genotyping, Strains, Isolation, Mutations, In vitro, Cultivation, Africa-General",

author = "F.E. Graf and P. Ludin and T. Wenzler and M. Kaiser and R. Brun and P.P. Pyana and P. B{\"u}scher and \{de Koning\}, H.P. and D. Horn and P. M{\"a}ser",

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TY - JOUR

T1 - Aquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprol

AU - Graf, F.E.

AU - Ludin, P.

AU - Wenzler, T.

AU - Kaiser, M.

AU - Brun, R.

AU - Pyana, P.P.

AU - Büscher, P.

AU - de Koning, H.P.

AU - Horn, D.

AU - Mäser, P.

N1 - ITG-B6B; ITG-B7A; DBM; U-PARDIA; JIF; DOI; PDF; E-only; DSPACE56 FTX

PY - 2013

Y1 - 2013

KW - Protozoal diseases

KW - Sleeping sickness

KW - Trypanosomiasis-African

KW - Trypanosoma brucei gambiense

KW - Trypanosoma brucei rhodesiense

KW - Vectors

KW - Tsetse flies

KW - Glossina morsitans

KW - Drug susceptibility

KW - Drug resistance

KW - Pentamidine

KW - Melarsoprol

KW - Sensitivity

KW - Phenotyping

KW - Genotyping

KW - Strains

KW - Isolation

KW - Mutations

KW - In vitro

KW - Cultivation

KW - Africa-General

U2 - 10.1371/journal.pntd.0002475

DO - 10.1371/journal.pntd.0002475

M3 - A1: Peer-reviewed journal articles

SN - 1935-2727

VL - 7

SP - e2475

JO - PLoS Neglected Tropical Diseases

JF - PLoS Neglected Tropical Diseases

IS - 10

ER -