Association between a social-business eating pattern and early asymptomatic atherosclerosis

José L Peñalvo; Leticia Fernández-Friera; Beatriz López-Melgar; Irina Uzhova; Belén Oliva; Juan Miguel Fernández-Alvira; Martín Laclaustra; Stuart Pocock; Agustín Mocoroa; José M Mendiguren; Ginés Sanz; Eliseo Guallar; Sameer Bansilal; Rajesh Vedanthan; Luis Jesús Jiménez-Borreguero; Borja Ibañez; José M Ordovás; Antonio Fernández-Ortiz; Héctor Bueno; Valentin Fuster

doi:10.1016/j.jacc.2016.05.080

Association between a social-business eating pattern and early asymptomatic atherosclerosis

José L Peñalvo, Leticia Fernández-Friera, Beatriz López-Melgar, Irina Uzhova, Belén Oliva, Juan Miguel Fernández-Alvira, Martín Laclaustra, Stuart Pocock, Agustín Mocoroa, José M Mendiguren, Ginés Sanz, Eliseo Guallar, Sameer Bansilal, Rajesh Vedanthan, Luis Jesús Jiménez-Borreguero, Borja Ibañez, José M Ordovás, Antonio Fernández-Ortiz, Héctor Bueno, Valentin Fuster

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

BACKGROUND: The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies.

OBJECTIVES: This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults.

METHODS: The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information.

RESULTS: Most PESA participants follow a Mediterranean (40% of participants) or a Western (41%) dietary pattern. A new pattern, identified among 19% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet.

CONCLUSIONS: A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318).

Original language	English
Journal	Journal of the American College of Cardiology
Volume	68
Issue number	8
Pages (from-to)	805-14
Number of pages	10
ISSN	0735-1097
DOIs	https://doi.org/10.1016/j.jacc.2016.05.080
Publication status	Published - 2016
Externally published	Yes

Keywords

Adult
Asymptomatic Diseases
Atherosclerosis/epidemiology
Cross-Sectional Studies
Diet/methods
Feeding Behavior
Female
Follow-Up Studies
Humans
Life Style
Male
Middle Aged
Morbidity/trends
Prevalence
Primary Prevention/methods
Prospective Studies
Risk Factors
Spain/epidemiology
Time Factors

Access to Document

10.1016/j.jacc.2016.05.080

Cite this

Peñalvo, J. L., Fernández-Friera, L., López-Melgar, B., Uzhova, I., Oliva, B., Fernández-Alvira, J. M., Laclaustra, M., Pocock, S., Mocoroa, A., Mendiguren, J. M., Sanz, G., Guallar, E., Bansilal, S., Vedanthan, R., Jiménez-Borreguero, L. J., Ibañez, B., Ordovás, J. M., Fernández-Ortiz, A., Bueno, H., & Fuster, V. (2016). Association between a social-business eating pattern and early asymptomatic atherosclerosis. Journal of the American College of Cardiology, 68(8), 805-14. https://doi.org/10.1016/j.jacc.2016.05.080

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title = "Association between a social-business eating pattern and early asymptomatic atherosclerosis",

abstract = "BACKGROUND: The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies.OBJECTIVES: This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults.METHODS: The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information.RESULTS: Most PESA participants follow a Mediterranean (40% of participants) or a Western (41%) dietary pattern. A new pattern, identified among 19% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet.CONCLUSIONS: A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318).",

keywords = "Adult, Asymptomatic Diseases, Atherosclerosis/epidemiology, Cross-Sectional Studies, Diet/methods, Feeding Behavior, Female, Follow-Up Studies, Humans, Life Style, Male, Middle Aged, Morbidity/trends, Prevalence, Primary Prevention/methods, Prospective Studies, Risk Factors, Spain/epidemiology, Time Factors",

author = "Pe{\~n}alvo, {Jos{\'e} L} and Leticia Fern{\'a}ndez-Friera and Beatriz L{\'o}pez-Melgar and Irina Uzhova and Bel{\'e}n Oliva and Fern{\'a}ndez-Alvira, {Juan Miguel} and Mart{\'i}n Laclaustra and Stuart Pocock and Agust{\'i}n Mocoroa and Mendiguren, {Jos{\'e} M} and Gin{\'e}s Sanz and Eliseo Guallar and Sameer Bansilal and Rajesh Vedanthan and Jim{\'e}nez-Borreguero, {Luis Jes{\'u}s} and Borja Iba{\~n}ez and Ordov{\'a}s, {Jos{\'e} M} and Antonio Fern{\'a}ndez-Ortiz and H{\'e}ctor Bueno and Valentin Fuster",

year = "2016",

doi = "10.1016/j.jacc.2016.05.080",

language = "English",

volume = "68",

pages = "805--14",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier",

number = "8",

}

Peñalvo, JL, Fernández-Friera, L, López-Melgar, B, Uzhova, I, Oliva, B, Fernández-Alvira, JM, Laclaustra, M, Pocock, S, Mocoroa, A, Mendiguren, JM, Sanz, G, Guallar, E, Bansilal, S, Vedanthan, R, Jiménez-Borreguero, LJ, Ibañez, B, Ordovás, JM, Fernández-Ortiz, A, Bueno, H & Fuster, V 2016, 'Association between a social-business eating pattern and early asymptomatic atherosclerosis', Journal of the American College of Cardiology, vol. 68, no. 8, pp. 805-14. https://doi.org/10.1016/j.jacc.2016.05.080

TY - JOUR

T1 - Association between a social-business eating pattern and early asymptomatic atherosclerosis

AU - Peñalvo, José L

AU - Fernández-Friera, Leticia

AU - López-Melgar, Beatriz

AU - Uzhova, Irina

AU - Oliva, Belén

AU - Fernández-Alvira, Juan Miguel

AU - Laclaustra, Martín

AU - Pocock, Stuart

AU - Mocoroa, Agustín

AU - Mendiguren, José M

AU - Sanz, Ginés

AU - Guallar, Eliseo

AU - Bansilal, Sameer

AU - Vedanthan, Rajesh

AU - Jiménez-Borreguero, Luis Jesús

AU - Ibañez, Borja

AU - Ordovás, José M

AU - Fernández-Ortiz, Antonio

AU - Bueno, Héctor

AU - Fuster, Valentin

PY - 2016

Y1 - 2016

N2 - BACKGROUND: The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies.OBJECTIVES: This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults.METHODS: The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information.RESULTS: Most PESA participants follow a Mediterranean (40% of participants) or a Western (41%) dietary pattern. A new pattern, identified among 19% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet.CONCLUSIONS: A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318).

AB - BACKGROUND: The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies.OBJECTIVES: This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults.METHODS: The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information.RESULTS: Most PESA participants follow a Mediterranean (40% of participants) or a Western (41%) dietary pattern. A new pattern, identified among 19% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet.CONCLUSIONS: A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318).

KW - Adult

KW - Asymptomatic Diseases

KW - Atherosclerosis/epidemiology

KW - Cross-Sectional Studies

KW - Diet/methods

KW - Feeding Behavior

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Life Style

KW - Male

KW - Middle Aged

KW - Morbidity/trends

KW - Prevalence

KW - Primary Prevention/methods

KW - Prospective Studies

KW - Risk Factors

KW - Spain/epidemiology

KW - Time Factors

U2 - 10.1016/j.jacc.2016.05.080

DO - 10.1016/j.jacc.2016.05.080

M3 - A1: Web of Science-article

C2 - 27539172

SN - 0735-1097

VL - 68

SP - 805

EP - 814

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 8

ER -

Association between a social-business eating pattern and early asymptomatic atherosclerosis

Abstract

Keywords

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