Automated, laboratory-based system using the Internet for disease outbreak detection, the Netherlands

Marc-Alain Widdowson, Arnold Bosman, Edward van Straten, Mark Tinga, Sandra Chaves, Liesbeth van Eerden, Wilfred van Pelt

Research output: Contribution to journalA1: Web of Science-articlepeer-review


Rapid detection of outbreaks is recognized as crucial for effective control measures and has particular relevance with the recently increased concern about bioterrorism. Automated analysis of electronically collected laboratory data can result in rapid detection of widespread outbreaks or outbreaks of pathogens with common signs and symptoms. In the Netherlands, an automated outbreak detection system for all types of pathogens has been developed within an existing electronic laboratory-based surveillance system called ISIS. Features include the use of a flexible algorithm for daily analysis of data and presentation of signals on the Internet for interpretation by health professionals. By 2006, the outbreak detection system will analyze laboratory-reported data on all pathogens and will cover 35% of the Dutch population.

Original languageEnglish
JournalEmerging Infectious Diseases
Issue number9
Pages (from-to)1046-1052
Number of pages7
Publication statusPublished - 2003


  • Algorithms
  • Bacteria/classification
  • Clinical Laboratory Techniques/statistics & numerical data
  • Communicable Diseases, Emerging/diagnosis
  • Disease Outbreaks
  • Humans
  • Internet
  • Netherlands/epidemiology
  • Population Surveillance/methods


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