Canine Trypanosoma evansi infection introduced into Germany

M. Defontis, J. Richartz, N. Engelmann, C. Bauer, V.M. Schwierk, Philippe Büscher, A. Moritz

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    A 9-year-old male Jack Russell Terrier with a history of travel to Thailand was presented with chronic lethargy, weight loss, unilateral anterior uveitis, pancytopenia, hyperglobulinemia, and proteinuria. Numerous trypomastigotes were found on a blood smear, and using molecular methods the parasite was identified as Trypanosoma evansi. After initial response to treatment, the dog experienced a relapse with central neurologic signs 88 days after initial presentation and died. Antibodies to T evansi were detected in both serum and cerebrospinal fluid (CSF) using a card agglutination test (CATT/T evansi), and PCR analysis of CSF for T evansi was positive. Findings at necropsy included marked non-purulent meningoencephalitis. Chronic infection with T evansi in a dog that returned to Germany following international travel highlights the risk associated with introduction of foreign animal diseases to Europe and the possibility of these infections becoming endemic. Detection of chronic infection and curative therapy of trypanosomiasis are challenging, and infection is usually fatal in the dog.
    Original languageEnglish
    JournalVeterinary Clinical Pathology
    Volume41
    Issue number3
    Pages (from-to)369-374
    Number of pages6
    ISSN0275-6382
    DOIs
    Publication statusPublished - 2012

    Keywords

    • Protozoal diseases
    • Surra
    • Trypanosoma evansi
    • Vectors
    • Tsetse flies
    • Glossina
    • Tabanidae
    • Stomoxys
    • Haematopota
    • Chrysops
    • Lyperosia
    • Dogs
    • Travel medicine
    • Case reports
    • Clinical manifestations
    • Diagnosis
    • Treatment
    • Relapses
    • Neurology
    • Meningoencephalitis
    • Mortality
    • Thailand
    • Asia-Southeast
    • Germany
    • Europe-West

    Fingerprint

    Dive into the research topics of 'Canine <i>Trypanosoma evansi</i> infection introduced into Germany'. Together they form a unique fingerprint.

    Cite this