TY - JOUR
T1 - Characterization of ESBL-producing Salmonella enterica serovar infantis infection in humans, Lima, Peru
AU - SalmoIber CYTED Network
AU - Garcia, Coralith
AU - Hinostroza, Noemi
AU - Astocondor, Lizeth
AU - Ochoa, Theresa
AU - Jacobs, Jan
AU - Soncini, Fernando
AU - Garcia-Vescovi, Eleonora
AU - Soleto, Lorena
AU - Flores, Griselda
AU - Pedraza, Jose
AU - Silva, Claudia
AU - Puente, Jose
AU - Betancor, Laura
AU - Yim, Lucia
AU - Alejandro, Jose
AU - Pucciarelli, M. Graciela
AU - Garcia-Del Portillo, Francisco
N1 - NPP
PY - 2019
Y1 - 2019
N2 - Salmonella enterica serovar Infantis is causing an increasing number of infections worldwide. Our aim was to describe the characteristics of S. enterica serovar Infantis among patients attended in a hospital of Lima, Peru. Fifty cases of salmonellosis were seen during October 2015-May 2017; Salmonella Infantis was detected in 36% (n = 18) of them, displacing Enteritidis and Typhimurium (n = 13, 26%, each). Seventeen cases caused by Salmonella Infantis were presented as diarrheal illnesses; only one extraintestinal case (bacteremia) was seen in a 1-year-old infant. This serovar is resistant to multiple groups of antimicrobials, showing only fully susceptibility to carbapenems. Compared with Infantis, other serovars analyzed (mainly Enteritidis and Typhimurium) showed a lower frequency of resistance to antimicrobials such as trimethoprim-sulfamethoxazole, ampicillin, and chloramphenicol. The antibiotic with the highest frequency of resistance was ciprofloxacin. Further studies are needed to evaluate the routes of transmission and measures of control of this multidrug-resistant Salmonella.
AB - Salmonella enterica serovar Infantis is causing an increasing number of infections worldwide. Our aim was to describe the characteristics of S. enterica serovar Infantis among patients attended in a hospital of Lima, Peru. Fifty cases of salmonellosis were seen during October 2015-May 2017; Salmonella Infantis was detected in 36% (n = 18) of them, displacing Enteritidis and Typhimurium (n = 13, 26%, each). Seventeen cases caused by Salmonella Infantis were presented as diarrheal illnesses; only one extraintestinal case (bacteremia) was seen in a 1-year-old infant. This serovar is resistant to multiple groups of antimicrobials, showing only fully susceptibility to carbapenems. Compared with Infantis, other serovars analyzed (mainly Enteritidis and Typhimurium) showed a lower frequency of resistance to antimicrobials such as trimethoprim-sulfamethoxazole, ampicillin, and chloramphenicol. The antibiotic with the highest frequency of resistance was ciprofloxacin. Further studies are needed to evaluate the routes of transmission and measures of control of this multidrug-resistant Salmonella.
KW - SPECTRUM BETA-LACTAMASE
KW - CTX-M-65
KW - GENES
KW - RESISTANCE
U2 - 10.4269/ajtmh.19-0213
DO - 10.4269/ajtmh.19-0213
M3 - A1: Web of Science-article
SN - 0002-9637
VL - 101
SP - 746
EP - 748
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 4
ER -