Chlorhexidine mouthwash fails to eradicate oropharyngeal gonorrhea in a clinical pilot trial (MoNg)

Christophe Van Dijck; Achilleas Tsoumanis; Annelies De Hondt; Vicky Cuylaerts; Jolein Laumen; Yven Van Herrewege; Eric Florence; Irith De Baetselier; Chris Kenyon

doi:10.1097/OLQ.0000000000001515

Chlorhexidine mouthwash fails to eradicate oropharyngeal gonorrhea in a clinical pilot trial (MoNg)

Research output: Contribution to journal › A1: Peer-reviewed journal articles › peer-review

Abstract

ABSTRACT: This single-arm open-label pilot trial in Antwerp, Belgium was ended early in accordance with the protocol since twice daily gargling with chlorhexidine 0.2% for six days failed to eradicate Neisseria gonorrhoeae from the oropharynx of asymptomatic men who have sex with men (n = 3, efficacy of 0%, 95% CI 0 - 56.1%).

Original language	English
Journal	Sexually Transmitted Diseases
Volume	49
Issue number	2
Pages (from-to)	e38-e41
ISSN	0148-5717
DOIs	https://doi.org/10.1097/OLQ.0000000000001515
Publication status	Published - 2021

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10.1097/OLQ.0000000000001515

Resistance in gonorrhoea
Van Dijck, C. (PhD Student), Kenyon, C. (Promotor) & Malhotra-Kumar, S. (Promotor)
3/07/19 → 13/12/22
Project: PhD-project

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@article{517602898539478cac36949ca1d023fa,

title = "Chlorhexidine mouthwash fails to eradicate oropharyngeal gonorrhea in a clinical pilot trial (MoNg)",

abstract = "ABSTRACT: This single-arm open-label pilot trial in Antwerp, Belgium was ended early in accordance with the protocol since twice daily gargling with chlorhexidine 0.2\% for six days failed to eradicate Neisseria gonorrhoeae from the oropharynx of asymptomatic men who have sex with men (n = 3, efficacy of 0\%, 95\% CI 0 - 56.1\%).",

author = "\{Van Dijck\}, Christophe and Achilleas Tsoumanis and \{De Hondt\}, Annelies and Vicky Cuylaerts and Jolein Laumen and \{Van Herrewege\}, Yven and Eric Florence and \{De Baetselier\}, Irith and Chris Kenyon",

note = "NPP; Copyright {\textcopyright}2021 American Sexually Transmitted Diseases Association.",

year = "2021",

doi = "10.1097/OLQ.0000000000001515",

language = "English",

volume = "49",

pages = "e38--e41",

journal = "Sexually Transmitted Diseases",

issn = "0148-5717",

publisher = "Lippincott Williams \& Wilkins",

number = "2",

}

TY - JOUR

T1 - Chlorhexidine mouthwash fails to eradicate oropharyngeal gonorrhea in a clinical pilot trial (MoNg)

AU - Van Dijck, Christophe

AU - Tsoumanis, Achilleas

AU - De Hondt, Annelies

AU - Cuylaerts, Vicky

AU - Laumen, Jolein

AU - Van Herrewege, Yven

AU - Florence, Eric

AU - De Baetselier, Irith

AU - Kenyon, Chris

PY - 2021

Y1 - 2021

N2 - ABSTRACT: This single-arm open-label pilot trial in Antwerp, Belgium was ended early in accordance with the protocol since twice daily gargling with chlorhexidine 0.2% for six days failed to eradicate Neisseria gonorrhoeae from the oropharynx of asymptomatic men who have sex with men (n = 3, efficacy of 0%, 95% CI 0 - 56.1%).

AB - ABSTRACT: This single-arm open-label pilot trial in Antwerp, Belgium was ended early in accordance with the protocol since twice daily gargling with chlorhexidine 0.2% for six days failed to eradicate Neisseria gonorrhoeae from the oropharynx of asymptomatic men who have sex with men (n = 3, efficacy of 0%, 95% CI 0 - 56.1%).

U2 - 10.1097/OLQ.0000000000001515

DO - 10.1097/OLQ.0000000000001515

M3 - A1: Peer-reviewed journal articles

C2 - 34282741

SN - 0148-5717

VL - 49

SP - e38-e41

JO - Sexually Transmitted Diseases

JF - Sexually Transmitted Diseases

IS - 2

ER -

Chlorhexidine mouthwash fails to eradicate oropharyngeal gonorrhea in a clinical pilot trial (MoNg)

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Resistance in gonorrhoea

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