TY - JOUR
T1 - Circulating anodic and cathodic antigen in serum and urine of mixed Schistosoma haematobium and S. mansoni infections in Office du Niger, Mali
AU - De Clercq, D
AU - Sacko, M
AU - Vercruysse, J
AU - Landouré, A
AU - Diarra, A
AU - Gryseels, B
AU - Deelder, A
AU - Vanden Bussche, Vincent
N1 - FTX abonnement
PY - 1997
Y1 - 1997
N2 - In Office du Niger, an area endemic for both Schistosoma haematobium and S. mansoni in Mali, circulating anodic (CAA) and cathodic (CCA) antigen detection assays were performed on pre-treatment serum and urine samples from two villages, Rigandé and Siguivoucé, and compared with egg counting methods. The highest prevalence was obtained with the urine-CCA assay which also had the highest sensitivity to S. haematobium, S. mansoni or mixed infection. A single urine-CCA assay was as sensitive as repeated egg counts (one stool + two urine examinations per individual). When the different assays were tested in parallel, several combinations including assays on serum were found to be highly sensitive. As urine sampling is widely accepted, urine assays will be used for further monitoring these villages one and two years after chemotherapy.
AB - In Office du Niger, an area endemic for both Schistosoma haematobium and S. mansoni in Mali, circulating anodic (CAA) and cathodic (CCA) antigen detection assays were performed on pre-treatment serum and urine samples from two villages, Rigandé and Siguivoucé, and compared with egg counting methods. The highest prevalence was obtained with the urine-CCA assay which also had the highest sensitivity to S. haematobium, S. mansoni or mixed infection. A single urine-CCA assay was as sensitive as repeated egg counts (one stool + two urine examinations per individual). When the different assays were tested in parallel, several combinations including assays on serum were found to be highly sensitive. As urine sampling is widely accepted, urine assays will be used for further monitoring these villages one and two years after chemotherapy.
KW - B780-tropical-medicine
KW - Helminthic diseases
KW - Mixed infections
KW - Schistosoma haematobium
KW - Schistosoma mansoni
KW - Circulating antigens
KW - Serum
KW - Urine
KW - Laboratory techniques and procedures
KW - Mali
KW - Africa-West
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:A1997XM65800010
U2 - 10.1046/j.1365-3156.1997.d01-354.x
DO - 10.1046/j.1365-3156.1997.d01-354.x
M3 - A1: Web of Science-article
SN - 1360-2276
VL - 2
SP - 680
EP - 685
JO - Tropical Medicine and International Health
JF - Tropical Medicine and International Health
IS - 7
ER -