Complexities in using sentinel pigs to study Taenia solium transmission dynamics under field conditions

B. Devleesschauwer, A. Aryal, J. Tharmalingam, D.D. Joshi, S. Rijal, N. Speybroeck, S. Gabriël, B. Victor, P. Dorny

Research output: Contribution to journalA1: Web of Science-article

Abstract

The transmission dynamics of the pork tapeworm, Taenia solium, remain a matter of research and debate. In a longitudinal field study performed in southeastern Nepal, 18 sentinel pigs were serologically monitored to study the field kinetics of Taenia antigens and anti-T. solium antibodies. At the end of the twelve months' study period, necropsy was performed and suspected lesions were subjected to molecular identification of the Taenia species. The study generated new hypotheses on the transmission dynamics of Taenia spp. and exposed crucial complexities in the use of sentinel pigs in longitudinal field studies. Sentinel pigs can be useful epidemiological tools, but their use should be thoroughly planned before initiating a study and carefully monitored throughout the course of the study. Important aspects to be considered are those affecting the pig's susceptibility to infection, such as passive immunity, age, hormonal levels, and infection with competing Taenia species. In addition, serological test results should be interpreted considering possible cross-reactions and with proper understanding of the significance of a positive test result.
Original languageEnglish
JournalVeterinary Parasitology
Volume193
Issue number1-3
Pages (from-to)172-178
Number of pages7
ISSN0304-4017
DOIs
Publication statusPublished - 2013

Keywords

  • Helminthic diseases
  • Zoonoses
  • Neurocysticercosis
  • Epilepsy
  • Taenia solium
  • Taenia hydatigena
  • Pigs
  • Disease transmission
  • Transmission dynamics
  • Field research
  • Sentinel surveillance
  • Monitoring
  • Kinetics
  • Antigens
  • Antibodies
  • Necropsy
  • Lesions
  • Molecular confirmation
  • Methodology
  • Organization
  • Selection
  • Nepal
  • Asia-South
  • PDF

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