Control of viral replication after cessation of HAART

E Van Gulck, L Heyndrickx, L Bracke, S Coppens, E Florence, A Buvé, P Lewi, G Vanham

    Research output: Contribution to journalA4: Article in journal not included in A1, A2 or A3

    Abstract

    We describe two patients who did not experience a viral rebound after cessation of HAART which was initiated for progressive disease. CD4 T-cell count remained stable in one patient and progressively declined in the other, despite apparent viral control. We failed to identify any immune activation or genetic markers that could offer an explanation for this unusual 'secondary controller' status. But their viruses are clearly less fit compared to viruses from rebounders.
    Original languageEnglish
    JournalAIDS Research and Therapy
    Volume8
    Pages (from-to)6
    Number of pages5
    ISSN1742-6405
    DOIs
    Publication statusPublished - 2011

    Keywords

    • B780-tropical-medicine
    • Viral diseases
    • HIV
    • AIDS
    • HAART
    • Antiretrovirals
    • Treatment outcome
    • Viral load
    • Replication
    • Case reports
    • CD4 lymphocyte count
    • Viral fitness
    • Belgium
    • Europe-West

    Fingerprint

    Dive into the research topics of 'Control of viral replication after cessation of HAART'. Together they form a unique fingerprint.

    Cite this