TY - JOUR
T1 - Culture and drug susceptibility testing among previously treated tuberculosis patients in the Dominican Republic, 2014
AU - Mercado, Katia J Romero
AU - Marcelino, Belkys
AU - Rodríguez, María
AU - Verdonck, Kristien
AU - Khogali, Mohammed
AU - Bissell, Karen
N1 - FTX; DOAJ
PY - 2016
Y1 - 2016
N2 - Multidrug-resistant tuberculosis (MDR-TB) is a major public health concern that threatens global progress toward effective TB control. The risk of MDR-TB is increased in patients who have received previous TB treatment. This article describes the performance of culture and drug susceptibility testing (DST) in patients registered as previously treated TB patients in the Dominican Republic in 2014, based on operational research that followed a retrospective cohort design and used routine program data. Under the current system of TB culturing and DST, the majority of patients with previously treated TB do not undergo DST, and those who do often experience considerable delay in obtaining their results. The lack of DST and delay in receiving DST results leads to underestimation of the number of MDR-TB cases and hinders the timely initiation of MDR-TB treatment.
AB - Multidrug-resistant tuberculosis (MDR-TB) is a major public health concern that threatens global progress toward effective TB control. The risk of MDR-TB is increased in patients who have received previous TB treatment. This article describes the performance of culture and drug susceptibility testing (DST) in patients registered as previously treated TB patients in the Dominican Republic in 2014, based on operational research that followed a retrospective cohort design and used routine program data. Under the current system of TB culturing and DST, the majority of patients with previously treated TB do not undergo DST, and those who do often experience considerable delay in obtaining their results. The lack of DST and delay in receiving DST results leads to underestimation of the number of MDR-TB cases and hinders the timely initiation of MDR-TB treatment.
KW - Antitubercular Agents
KW - Dominican Republic
KW - Humans
KW - Microbial Sensitivity Tests
KW - Mycobacterium tuberculosis
KW - Retrospective Studies
KW - Tuberculosis
UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000378118900010
M3 - A1: Web of Science-article
C2 - 27754535
SN - 1020-4989
VL - 39
SP - 60
EP - 64
JO - Revista Panamericana de Salud Pública
JF - Revista Panamericana de Salud Pública
IS - 1
ER -