Daily fluctuation of levels of circulating cathodic antigen levels in urine of children infected with Schistosoma mansoni in Brazil

J Disch, MMA Garcia, GW Krijger, MN Amorim, N Karz, AM Deelder, B Gryseels, AA Rabello

Research output: Contribution to journalA1: Web of Science-articlepeer-review

Abstract

The fluctuation of circulating cathodic antigen (CCA) levels in urine was studied in 69 Brazilian school-children infected with Schistosoma mansoni and compared to egg counts. Faeces and urine samples were simultaneously collected at 7 times during a period of 2 weeks. CCA was determined by enzyme-linked immunosorbent assay and could be detected in 96% of the urine samples; the individual mean CCA level ranged from 609 to 350700 pg/mL. 90% of the faecal samples contained S. mansoni eggs and the individual mean egg output ranged from 9 to 5510 eggs/g. The Spearman rank correlation ceofficient between these individual means was 0·69. Kendal,s coefficient of concordance (W) was 0·88 for CCA levels and 0·80 for egg counts.
Original languageEnglish
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume91
Issue number2
Pages (from-to)222-225
Number of pages4
ISSN0035-9203
DOIs
Publication statusPublished - 1997

Keywords

  • B780-tropical-medicine
  • Helminthic diseases
  • Schistosomiasis
  • Schistosoma mansoni
  • Children
  • Cathodic antigen levels
  • Brazil
  • America-Latin

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