Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC

Florian Vogt; Lucien Kalenga; Jean Lukela; Freddy Salumu; Ibrahim Diallo; Elena Nico; Emmanuel Lampart; Rafael Van den Bergh; Safieh Shah; Olumide Ogundahunsi; Rony Zachariah; Johan Van Griensven

doi:10.1097/QAI.0000000000001215

Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC

Florian Vogt, Lucien Kalenga, Jean Lukela, Freddy Salumu, Ibrahim Diallo, Elena Nico, Emmanuel Lampart, Rafael Van den Bergh, Safieh Shah, Olumide Ogundahunsi, Rony Zachariah, Johan Van Griensven

Neglected Tropical Diseases

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to followup, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with > 3 years on ART,> 500 cluster of differentiation type-4 count, body mass index > 18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage.

Original language	English
Journal	Journal of Acquired Immune Deficiency Syndromes
Volume	74
Issue number	3
Pages (from-to)	326-331
Number of pages	6
ISSN	1525-4135
DOIs	https://doi.org/10.1097/QAI.0000000000001215
Publication status	Published - 2017

Keywords

antiretroviral therapy
HIV
decentralization
task shifting
community
urban
SUB-SAHARAN AFRICA
ANTIRETROVIRAL TREATMENT OUTCOMES
MIDDLE-INCOME COUNTRIES
HIV/AIDS TREATMENT
PROSPECTIVE COHORT
CLINICAL-OUTCOMES
CARE PROGRAM
RURAL UGANDA
AIDS CARE
SCALE-UP

Access to Document

10.1097/QAI.0000000000001215

Cite this

Vogt, F., Kalenga, L., Lukela, J., Salumu, F., Diallo, I., Nico, E., Lampart, E., Van den Bergh, R., Shah, S., Ogundahunsi, O., Zachariah, R., & Van Griensven, J. (2017). Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC. Journal of Acquired Immune Deficiency Syndromes, 74(3), 326-331. https://doi.org/10.1097/QAI.0000000000001215

@article{d43e7df22b03414eaa61367e689640fd,

title = "Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC",

abstract = "Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to followup, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with > 3 years on ART,> 500 cluster of differentiation type-4 count, body mass index > 18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage.",

keywords = "antiretroviral therapy, HIV, decentralization, task shifting, community, urban, SUB-SAHARAN AFRICA, ANTIRETROVIRAL TREATMENT OUTCOMES, MIDDLE-INCOME COUNTRIES, HIV/AIDS TREATMENT, PROSPECTIVE COHORT, CLINICAL-OUTCOMES, CARE PROGRAM, RURAL UGANDA, AIDS CARE, SCALE-UP",

author = "Florian Vogt and Lucien Kalenga and Jean Lukela and Freddy Salumu and Ibrahim Diallo and Elena Nico and Emmanuel Lampart and {Van den Bergh}, Rafael and Safieh Shah and Olumide Ogundahunsi and Rony Zachariah and {Van Griensven}, Johan",

note = "NPP",

year = "2017",

doi = "10.1097/QAI.0000000000001215",

language = "English",

volume = "74",

pages = "326--331",

journal = "Journal of Acquired Immune Deficiency Syndromes",

issn = "1525-4135",

publisher = "Lippincott Williams & Wilkins",

number = "3",

}

Vogt, F, Kalenga, L, Lukela, J, Salumu, F, Diallo, I, Nico, E, Lampart, E, Van den Bergh, R, Shah, S, Ogundahunsi, O, Zachariah, R & Van Griensven, J 2017, 'Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC', Journal of Acquired Immune Deficiency Syndromes, vol. 74, no. 3, pp. 326-331. https://doi.org/10.1097/QAI.0000000000001215

Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC. / Vogt, Florian; Kalenga, Lucien; Lukela, Jean et al.
In: Journal of Acquired Immune Deficiency Syndromes, Vol. 74, No. 3, 2017, p. 326-331.

Research output: Contribution to journal › A1: Web of Science-article › peer-review

TY - JOUR

T1 - Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC

AU - Vogt, Florian

AU - Kalenga, Lucien

AU - Lukela, Jean

AU - Salumu, Freddy

AU - Diallo, Ibrahim

AU - Nico, Elena

AU - Lampart, Emmanuel

AU - Van den Bergh, Rafael

AU - Shah, Safieh

AU - Ogundahunsi, Olumide

AU - Zachariah, Rony

AU - Van Griensven, Johan

N1 - NPP

PY - 2017

Y1 - 2017

N2 - Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to followup, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with > 3 years on ART,> 500 cluster of differentiation type-4 count, body mass index > 18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage.

AB - Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to followup, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with > 3 years on ART,> 500 cluster of differentiation type-4 count, body mass index > 18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage.

KW - antiretroviral therapy

KW - HIV

KW - decentralization

KW - task shifting

KW - community

KW - urban

KW - SUB-SAHARAN AFRICA

KW - ANTIRETROVIRAL TREATMENT OUTCOMES

KW - MIDDLE-INCOME COUNTRIES

KW - HIV/AIDS TREATMENT

KW - PROSPECTIVE COHORT

KW - CLINICAL-OUTCOMES

KW - CARE PROGRAM

KW - RURAL UGANDA

KW - AIDS CARE

KW - SCALE-UP

U2 - 10.1097/QAI.0000000000001215

DO - 10.1097/QAI.0000000000001215

M3 - A1: Web of Science-article

SN - 1525-4135

VL - 74

SP - 326

EP - 331

JO - Journal of Acquired Immune Deficiency Syndromes

JF - Journal of Acquired Immune Deficiency Syndromes

IS - 3

ER -

Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC

Abstract

Keywords

Access to Document

Fingerprint

Cite this