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Decentralizing ART supply for stable HIV patients to community-based distribution centers: program outcomes from an urban context in Kinshasa, DRC

  • Florian Vogt
  • , Lucien Kalenga
  • , Jean Lukela
  • , Freddy Salumu
  • , Ibrahim Diallo
  • , Elena Nico
  • , Emmanuel Lampart
  • , Rafael Van den Bergh
  • , Safieh Shah
  • , Olumide Ogundahunsi
  • , Rony Zachariah
  • , Johan Van Griensven

Research output: Contribution to journalA1: Peer-reviewed journal articlespeer-review

Abstract

Facility-based antiretroviral therapy (ART) provision for stable patients with HIV congests health services in resource-limited countries. We assessed outcomes and risk factors for attrition after decentralization to community-based ART refill centers among 2603 patients with HIV in Kinshasa, Democratic Republic of Congo, using a multilevel Poisson regression model. Death, loss to followup, and transfer out were 0.3%, 9.0%, and 0.7%, respectively, at 24 months. Overall attrition was 5.66/100 person-years. Patients with > 3 years on ART,> 500 cluster of differentiation type-4 count, body mass index > 18.5, and receiving nevirapine but not stavudine showed reduced attrition. ART refill centers are a promising task-shifting model in low-prevalence urban settings with high levels of stigma and poor ART coverage.

Original languageEnglish
JournalJournal of Acquired Immune Deficiency Syndromes
Volume74
Issue number3
Pages (from-to)326-331
Number of pages6
ISSN1525-4135
DOIs
Publication statusPublished - 2017

Keywords

  • antiretroviral therapy
  • HIV
  • decentralization
  • task shifting
  • community
  • urban
  • SUB-SAHARAN AFRICA
  • ANTIRETROVIRAL TREATMENT OUTCOMES
  • MIDDLE-INCOME COUNTRIES
  • HIV/AIDS TREATMENT
  • PROSPECTIVE COHORT
  • CLINICAL-OUTCOMES
  • CARE PROGRAM
  • RURAL UGANDA
  • AIDS CARE
  • SCALE-UP

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