Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]

A Drowart; CL Cambiaso; K Huygen; E Serruys; F Portaels; E Jann; JP Van Vooren

Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]

A Drowart, CL Cambiaso, K Huygen, E Serruys, F Portaels, E Jann, JP Van Vooren

Mycobacteriology

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

The particle agglutinated counting immunoassay (PACIA) was used to determine the susceptibility of Mycobacterium tuberculosis strains to the two major antimycobacterial drugs, isoniazid and rifampicin. On evaluating 12 M. tuberculosis strains with different sensitivities, our results were in complete accordance with those obtained using the well-known BACTEC system. The PACIA technique is automated and quite inexpensive. Interpretation of the test may be achieved in as little as five days.

Original language	English
Journal	International Journal of Tuberculosis and Lung Disease
Volume	1
Issue number	3
Pages (from-to)	284-288
Number of pages	5
ISSN	1027-3719
Publication status	Published - 1997

Keywords

B780-tropical-medicine
Bacteriology
Mycobacterium tuberculosis
Rifampicin
Isoniazid
Drug resistance
Drug sensitivity testing
Latex fixation tests
PACIA

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title = "Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]",

abstract = "The particle agglutinated counting immunoassay (PACIA) was used to determine the susceptibility of Mycobacterium tuberculosis strains to the two major antimycobacterial drugs, isoniazid and rifampicin. On evaluating 12 M. tuberculosis strains with different sensitivities, our results were in complete accordance with those obtained using the well-known BACTEC system. The PACIA technique is automated and quite inexpensive. Interpretation of the test may be achieved in as little as five days.",

keywords = "B780-tropical-medicine, Bacteriology, Mycobacterium tuberculosis, Rifampicin, Isoniazid, Drug resistance, Drug sensitivity testing, Latex fixation tests, PACIA",

author = "A Drowart and CL Cambiaso and K Huygen and E Serruys and F Portaels and E Jann and {Van Vooren}, JP",

note = "FTX: Abonnement",

year = "1997",

language = "English",

volume = "1",

pages = "284--288",

journal = "International Journal of Tuberculosis and Lung Disease",

issn = "1027-3719",

publisher = "International Union Against Tuberculosis and Lung Disease",

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}

Drowart, A, Cambiaso, CL, Huygen, K, Serruys, E, Portaels, F, Jann, E & Van Vooren, JP 1997, 'Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]', International Journal of Tuberculosis and Lung Disease, vol. 1, no. 3, pp. 284-288. <http://lib.itg.be/pdf/itg/1997/1997ijtl0284.pdf>

Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]. / Drowart, A; Cambiaso, CL; Huygen, K et al.
In: International Journal of Tuberculosis and Lung Disease, Vol. 1, No. 3, 1997, p. 284-288.

Research output: Contribution to journal › A1: Web of Science-article › peer-review

TY - JOUR

T1 - Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]

AU - Drowart, A

AU - Cambiaso, CL

AU - Huygen, K

AU - Serruys, E

AU - Portaels, F

AU - Jann, E

AU - Van Vooren, JP

N1 - FTX: Abonnement

PY - 1997

Y1 - 1997

N2 - The particle agglutinated counting immunoassay (PACIA) was used to determine the susceptibility of Mycobacterium tuberculosis strains to the two major antimycobacterial drugs, isoniazid and rifampicin. On evaluating 12 M. tuberculosis strains with different sensitivities, our results were in complete accordance with those obtained using the well-known BACTEC system. The PACIA technique is automated and quite inexpensive. Interpretation of the test may be achieved in as little as five days.

AB - The particle agglutinated counting immunoassay (PACIA) was used to determine the susceptibility of Mycobacterium tuberculosis strains to the two major antimycobacterial drugs, isoniazid and rifampicin. On evaluating 12 M. tuberculosis strains with different sensitivities, our results were in complete accordance with those obtained using the well-known BACTEC system. The PACIA technique is automated and quite inexpensive. Interpretation of the test may be achieved in as little as five days.

KW - B780-tropical-medicine

KW - Bacteriology

KW - Mycobacterium tuberculosis

KW - Rifampicin

KW - Isoniazid

KW - Drug resistance

KW - Drug sensitivity testing

KW - Latex fixation tests

KW - PACIA

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UR - https://www.ingentaconnect.com/contentone/iuatld/ijtld/1997/00000001/00000003/art00016

M3 - A1: Web of Science-article

SN - 1027-3719

VL - 1

SP - 284

EP - 288

JO - International Journal of Tuberculosis and Lung Disease

JF - International Journal of Tuberculosis and Lung Disease

IS - 3

ER -

Detection of rifampicin and isoniazid resistances of Mycobacterium tuberculosis strains by particle counting immunoassay (PACIA) [Technical Note]

Abstract

Keywords

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