TY - JOUR
T1 - Does mass drug administration for community-based scabies control works? The experience in Ethiopia
AU - Enbiale, Wendemagegn
AU - Ayalew, Ashenafi
AU - Gebrehiwot, Teklehaymanot
AU - Mulu, Yared
AU - Azage, Muluken
AU - Zachariah, Rony
AU - Romani, Lucia
AU - Verdonck, Kristien
AU - Van Griensven, Johan
AU - De Vries, Henry Jc
N1 - FTX; DOAJ; (CC BY 4.0); Copyright (c) 2020 Wendemagegn Enbiale, Ashenafi Ayalew , Teklehaymanot Gebrehiwot, Yared Mulu, Muluken Azage , Rony Zachariah, Lucia Romani, Kristien Verdonck, Johan van Griensven, Henry JC de Vries.
PY - 2020
Y1 - 2020
N2 - INTRODUCTION: After a scabies outbreak in Amhara Region, Ethiopia in 2015/2016, the Regional Health Bureau performed an extensive Mass Drug Administration (MDA). In May 2017, we collected data to assess the impact of the treatment on the scabies control.METHODOLOGY: We retrieved baseline data from the 2015/16 burden assessment: campaign organization and administration information. We did a community based cross-sectional study using a structured questionnaire on disease and treatment history plus the presence or absence of active scabies in three Zones. We selected households using stratified random sampling deployed 7581 questionnaires and performed key informant interviews.RESULTS: 46.3% had a previous scabies diagnosis in the last 2 years of which 86.1% received treatment, and the cure rate was 90.6%. Fifteen months after intervention the scabies prevalence was 21.0 % (67.3% new cases and 32.7% recurrences). The highest burden of new cases (93.1%) was found in the North Gondar zone. The likelihood of treatment failure was higher for treatments offered in clinics (12.2%) as opposed to via the campaign (7.9%). Failure to follow the guidelines, shortage of medicine and lack of leadership prioritization were identified as reasons for resurgence of the disease.CONCLUSIONS: We demonstrated that community engagement is essential in the success of scabies MDA, alongside strong political commitment, and guideline adherence. Effectiveness and sustainability of the MDA was compromised by the failing of proper contact treatment, surveillance and case management.
AB - INTRODUCTION: After a scabies outbreak in Amhara Region, Ethiopia in 2015/2016, the Regional Health Bureau performed an extensive Mass Drug Administration (MDA). In May 2017, we collected data to assess the impact of the treatment on the scabies control.METHODOLOGY: We retrieved baseline data from the 2015/16 burden assessment: campaign organization and administration information. We did a community based cross-sectional study using a structured questionnaire on disease and treatment history plus the presence or absence of active scabies in three Zones. We selected households using stratified random sampling deployed 7581 questionnaires and performed key informant interviews.RESULTS: 46.3% had a previous scabies diagnosis in the last 2 years of which 86.1% received treatment, and the cure rate was 90.6%. Fifteen months after intervention the scabies prevalence was 21.0 % (67.3% new cases and 32.7% recurrences). The highest burden of new cases (93.1%) was found in the North Gondar zone. The likelihood of treatment failure was higher for treatments offered in clinics (12.2%) as opposed to via the campaign (7.9%). Failure to follow the guidelines, shortage of medicine and lack of leadership prioritization were identified as reasons for resurgence of the disease.CONCLUSIONS: We demonstrated that community engagement is essential in the success of scabies MDA, alongside strong political commitment, and guideline adherence. Effectiveness and sustainability of the MDA was compromised by the failing of proper contact treatment, surveillance and case management.
U2 - 10.3855/jidc.11892
DO - 10.3855/jidc.11892
M3 - A1: Web of Science-article
C2 - 32614801
SN - 1972-2680
VL - 14
SP - 78S-85S
JO - Journal of Infection in Developing Countries
JF - Journal of Infection in Developing Countries
IS - 6(SI)
ER -