Ebola hemorrhagic fever and pregnancy

K Mupapa; W Mukundu; MA Bwaka; M Kipasa; A De Roo; K Kuvula; K Kibadi; M Massamba; D Ndaberey; R Colebunders; JJ Muyembe-Tamfum

doi:10.1086/514289

Ebola hemorrhagic fever and pregnancy

K Mupapa, W Mukundu, MA Bwaka, M Kipasa, A De Roo, K Kuvula, K Kibadi, M Massamba, D Ndaberey, R Colebunders, JJ Muyembe-Tamfum

Institute of Tropical Medicine

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).

Original language	English
Journal	Journal of Infectious Diseases
Volume	179
Issue number	Suppl.1
Pages (from-to)	S11-S12
Number of pages	2
ISSN	0022-1899
DOIs	https://doi.org/10.1086/514289
Publication status	Published - 1999

Keywords

B780-tropical-medicine
Viral diseases
Ebola virus disease
Pregnancy
Kikwit
Congo-Kinshasa
Africa-Central

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10.1086/514289

http://lib.itg.be/pdf/itg/1999/1999jidi0S11.pdf

Cite this

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title = "Ebola hemorrhagic fever and pregnancy",

abstract = "Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).",

keywords = "B780-tropical-medicine, Viral diseases, Ebola virus disease, Pregnancy, Kikwit, Congo-Kinshasa, Africa-Central",

author = "K Mupapa and W Mukundu and MA Bwaka and M Kipasa and {De Roo}, A and K Kuvula and K Kibadi and M Massamba and D Ndaberey and R Colebunders and JJ Muyembe-Tamfum",

note = "FTX: Abonnement",

year = "1999",

doi = "10.1086/514289",

language = "English",

volume = "179",

pages = "S11--S12",

journal = "Journal of Infectious Diseases",

issn = "0022-1899",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Ebola hemorrhagic fever and pregnancy

AU - Mupapa, K

AU - Mukundu, W

AU - Bwaka, MA

AU - Kipasa, M

AU - De Roo, A

AU - Kuvula, K

AU - Kibadi, K

AU - Massamba, M

AU - Ndaberey, D

AU - Colebunders, R

AU - Muyembe-Tamfum, JJ

N1 - FTX: Abonnement

PY - 1999

Y1 - 1999

N2 - Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).

AB - Fifteen (14%) of 105 women with Ebola hemorrhagic fever hospitalized in the isolation unit of the Kikwit General Hospital (Democratic Republic of the Congo) were pregnant. In 10 women (66%) the pregnancy ended with an abortion. In 3 of them, a curettage was performed, and all 3 received a blood transfusion from an apparently healthy person. One woman was prematurely delivered of a stillbirth. Four pregnant women died during the third trimester of their pregnancy. All women presented with severe bleeding. Only 1 survived; she had a curettage because of an incomplete abortion after 8 months of amenorrhea. The mortality among pregnant women with Ebola hemorrhagic fever (95.5%) was slightly but not significantly higher than the overall mortality observed during the Ebola epidemic in Kikwit (77%; 245/316 infected persons).

KW - B780-tropical-medicine

KW - Viral diseases

KW - Ebola virus disease

KW - Pregnancy

KW - Kikwit

KW - Congo-Kinshasa

KW - Africa-Central

UR - https://www.webofscience.com/wos/woscc/full-record/WOS:000078400300004

U2 - 10.1086/514289

DO - 10.1086/514289

M3 - A1: Web of Science-article

SN - 0022-1899

VL - 179

SP - S11-S12

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

IS - Suppl.1

ER -

Ebola hemorrhagic fever and pregnancy

Abstract

Keywords

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