Effect of antipyretics on performance of influenza surveillance in Ghana

Joseph Asamoah Frimpong, William Kwabena Ampofo, Kofi Mensah Nyarko, Jazmin Duque, James Aboagye, Kwadwo Koram, Marc-Alain Widdowson

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Background The World Health Organization's case definition for influenza-like illness (ILI) includes a measured temperature of >= 38 degrees C. We conducted this study to assess the effect of antipyretics on performance of ILI surveillance in Ghana. Methods A cross-sectional study was conducted in two districts of Ghana from September 2013 to May 2014. We collected epidemiological data and respiratory specimens from an expanded ILI case definition, which included patients presenting to health facilities with measured temperature >= 38 degrees C or reported fever (but afebrile at the time of evaluation), and cough, with onset in the last 10 days. Specimens were tested for influenza viruses by real time reverse-transcription polymerase chain reaction. Results Of 321 participants who met our expanded ILI case definition, 236 presented with temperature of

Original languageEnglish
Article numbere13068
JournalInfluenza and Other Respiratory Viruses
Issue number1
Number of pages5
Publication statusE-pub ahead of print - 2022


  • case definition
  • fever
  • influenza


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