Abstract
The efficacy of ivermectin and isometamidium chloride on survival, reproduction and infection rate was evaluated in Glossina palpalis palpalis (Robineau-Desvoidy) infected with Trypanosoma brucei brucei. Females fed permanently on ivermectin treated hosts - solely or in combination with isometamidium chloride - produced significantly fewer and lighter pupae compared with flies fed on untreated hosts. Disturbed pupariation was also observed in these series. Isometamidium chloride had no detectable effect upon survival or reproduction. No synergytic or antagonistic action of the two chemotherapeutic agents was observed. The overall infection rate with T. brucei brucei was unexpectedly low. No differences between experimental and control flies were observed.
| Original language | English |
|---|---|
| Journal | Annales de la Société Belge de Médecine Tropicale |
| Volume | 68 |
| Pages (from-to) | 53-59 |
| ISSN | 0365-6527 |
| Publication status | Published - 1988 |
Keywords
- B780-tropical-medicine
- Glossina palpalis
- Entomology
- Laboratory
- Ivermectin
- Isometamidium chloride
- Survival
- Reproduction
- Trypanosoma brucei
- Protozoology