TY - JOUR
T1 - Efficiency of field laboratories for Ebola virus disease outbreak during chronic insecurity, eastern Democratic Republic of the Congo, 2018-2020
AU - Mukadi-Bamuleka, Daniel
AU - Mambu-Mbika, Fabrice
AU - De Weggheleire, Anja
AU - Edidi-Atani, François
AU - Bulabula-Penge, Junior
AU - Mfumu, Meris Matondo Kua
AU - Legand, Anaïs
AU - Nkuba-Ndaye, Antoine
AU - N'kasar, Yannick Tutu Tshia
AU - Mbala-Kingebeni, Placide
AU - Klena, John D
AU - Montgomery, Joel M
AU - Muyembe-Tamfum, Jean-Jacques
AU - Formenty, Pierre
AU - van Griensven, Johan
AU - Ariën, Kevin K
AU - Ahuka-Mundeke, Steve
N1 - CPDF
PY - 2023
Y1 - 2023
N2 - During the 10th outbreak of Ebola virus disease in the Democratic Republic of the Congo, the Institut National de Recherche Biomédicale strategically positioned 13 decentralized field laboratories with dedicated equipment to quickly detect cases as the outbreak evolved. The laboratories were operated by national staff, who quickly handed over competencies and skills to local persons to successfully manage future outbreaks. Laboratories analyzed ≈230,000 Ebola diagnostic samples under stringent biosafety measures, documentation, and database management. Field laboratories diversified their activities (diagnosis, chemistry and hematology, survivor follow-up, and genomic sequencing) and shipped 127,993 samples from the field to a biorepository in Kinshasa under good conditions. Deploying decentralized and well-equipped laboratories run by local personnel in at-risk countries for Ebola virus disease outbreaks is an efficient response; all activities are quickly conducted in the field.
AB - During the 10th outbreak of Ebola virus disease in the Democratic Republic of the Congo, the Institut National de Recherche Biomédicale strategically positioned 13 decentralized field laboratories with dedicated equipment to quickly detect cases as the outbreak evolved. The laboratories were operated by national staff, who quickly handed over competencies and skills to local persons to successfully manage future outbreaks. Laboratories analyzed ≈230,000 Ebola diagnostic samples under stringent biosafety measures, documentation, and database management. Field laboratories diversified their activities (diagnosis, chemistry and hematology, survivor follow-up, and genomic sequencing) and shipped 127,993 samples from the field to a biorepository in Kinshasa under good conditions. Deploying decentralized and well-equipped laboratories run by local personnel in at-risk countries for Ebola virus disease outbreaks is an efficient response; all activities are quickly conducted in the field.
KW - Humans
KW - Hemorrhagic Fever, Ebola/diagnosis
KW - Ebolavirus/genetics
KW - Laboratories
KW - Democratic Republic of the Congo/epidemiology
KW - Disease Outbreaks
U2 - 10.3201/eid2901.221025
DO - 10.3201/eid2901.221025
M3 - A1: Web of Science-article
C2 - 36573642
VL - 29
SP - 1
EP - 9
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
SN - 1080-6040
IS - 1
ER -