Elimination of visceral leishmaniasis on the Indian subcontinent

Om Prakash Singh, Epco Hasker, Marleen Boelaert, Shyam Sundar

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    Visceral leishmaniasis is a serious public health problem on the Indian subcontinent, causing high morbidity and mortality. The governments in the region launched a visceral leishmaniasis elimination initiative in 2005. We review knowledge gaps and research priorities. Key challenges include low coverage of health services for those most at risk, drug resistance, the absence of a vaccine, and the complex biology of the sandfly-human host transmission cycle. Vector control is an essential component, but innovation in this field is insufficient. Substantial progress has been made in the area of diagnostic, therapeutic, and vaccine development, but there are still many hurdles to overcome. For visceral leishmaniasis elimination to become a reality, effective deployment of these existing and new tools is essential. A strong commitment at community level is imperative, and appropriate diagnostic and treatment services as well as effective epidemiological surveillance need to be ensured.

    Original languageEnglish
    JournalLancet Infectious Diseases
    Volume16
    Issue number2
    Pages (from-to)e304-e309
    Number of pages6
    ISSN1473-3099
    DOIs
    Publication statusPublished - 2016

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