Brucella abortus is prevalent in both humans and animals in Bangladesh

A. K. M. A. Rahman, C. Saegerman, D. Berkvens, F. Melzer, H. Neubauer, D. Fretin, E. Abatih, N. Dhand, M. P. Ward

    Research output: Contribution to journalA1: Web of Science-article

    Abstract

    To determine the role of different Brucella (B.) spp. in Bangladesh, 62 animal samples and 500 human sera were tested. Animal samples from cattle, goats and sheep (including milk, bull semen, vaginal swabs and placentas) were cultured for Brucella spp. Three test-positive human sera and all animal samples were screened by Brucella genus-specific real-time PCR (RT-PCR), and positive samples were then tested by IS711 RT-PCR to detect B.abortus and B.melitensis DNA. Only B.abortus DNA was amplified from 13 human and six animal samples. This is the first report describing B.abortus as the aetiological agent of brucellosis in occupationally exposed humans in Bangladesh. Of note is failure to detect B.melitensis DNA, the species most often associated with human brucellosis worldwide. Further studies are required to explore the occurrence of Brucella melitensis in Bangladesh.

    Original languageEnglish
    JournalZoonoses and Public Health
    Volume64
    Issue number5
    Pages (from-to)394-399
    Number of pages6
    ISSN1863-1959
    DOIs
    Publication statusPublished - 2017

    Keywords

    • Brucella abortus
    • humans
    • animals
    • clinical samples
    • Bangladesh
    • real-time PCR
    • POLYMERASE-CHAIN-REACTION
    • RISK-FACTORS
    • PCR ASSAY
    • SEROPREVALENCE
    • MELITENSIS
    • DIAGNOSIS
    • IS711
    • SERUM
    • SPP.

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