Emerging group-A rotavirus and a nosocomial outbreak of diarrhoea

M A Widdowson; G J van Doornum; W H van der Poel; A S de Boer; U Mahdi; M Koopmans

doi:10.1016/S0140-6736(00)02760-4

Emerging group-A rotavirus and a nosocomial outbreak of diarrhoea

M A Widdowson, G J van Doornum, W H van der Poel, A S de Boer, U Mahdi, M Koopmans

Institute of Tropical Medicine

Research output: Contribution to journal › A1: Web of Science-article › peer-review

Abstract

A P[6]G9 group-A rotavirus caused a protracted hospital outbreak of neonatal diarrhoea in The Netherlands. The outbreak lasted 5 months with 52 cases and an average attack rate of 40%, 46 cases were in an incubator section for neonates under 1 month of age. Rotavirus P161G9 was detected by RT-PCR in stool samples from the 31 cases tested. Emergence of this genotype in Europe may have implications for neonates lacking protective maternal antibodies and for the development of rotavirus vaccines.

Original language	English
Journal	Lancet
Volume	356
Issue number	9236
Pages (from-to)	1161-1162
Number of pages	2
ISSN	0140-6736
DOIs	https://doi.org/10.1016/S0140-6736(00)02760-4
Publication status	Published - 2000

Keywords

Cross Infection/diagnosis
Diarrhea, Infantile/diagnosis
Disease Outbreaks
Feces/virology
Female
Genotype
Humans
Infant, Newborn
Latex Fixation Tests
Male
Netherlands/epidemiology
Rotavirus/genetics
Rotavirus Infections/diagnosis

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10.1016/S0140-6736(00)02760-4

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title = "Emerging group-A rotavirus and a nosocomial outbreak of diarrhoea",

abstract = "A P[6]G9 group-A rotavirus caused a protracted hospital outbreak of neonatal diarrhoea in The Netherlands. The outbreak lasted 5 months with 52 cases and an average attack rate of 40%, 46 cases were in an incubator section for neonates under 1 month of age. Rotavirus P161G9 was detected by RT-PCR in stool samples from the 31 cases tested. Emergence of this genotype in Europe may have implications for neonates lacking protective maternal antibodies and for the development of rotavirus vaccines.",

keywords = "Cross Infection/diagnosis, Diarrhea, Infantile/diagnosis, Disease Outbreaks, Feces/virology, Female, Genotype, Humans, Infant, Newborn, Latex Fixation Tests, Male, Netherlands/epidemiology, Rotavirus/genetics, Rotavirus Infections/diagnosis",

author = "Widdowson, {M A} and {van Doornum}, {G J} and {van der Poel}, {W H} and {de Boer}, {A S} and U Mahdi and M Koopmans",

year = "2000",

doi = "10.1016/S0140-6736(00)02760-4",

language = "English",

volume = "356",

pages = "1161--1162",

journal = "Lancet",

issn = "0140-6736",

publisher = "Elsevier",

number = "9236",

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TY - JOUR

T1 - Emerging group-A rotavirus and a nosocomial outbreak of diarrhoea

AU - Widdowson, M A

AU - van Doornum, G J

AU - van der Poel, W H

AU - de Boer, A S

AU - Mahdi, U

AU - Koopmans, M

PY - 2000

Y1 - 2000

N2 - A P[6]G9 group-A rotavirus caused a protracted hospital outbreak of neonatal diarrhoea in The Netherlands. The outbreak lasted 5 months with 52 cases and an average attack rate of 40%, 46 cases were in an incubator section for neonates under 1 month of age. Rotavirus P161G9 was detected by RT-PCR in stool samples from the 31 cases tested. Emergence of this genotype in Europe may have implications for neonates lacking protective maternal antibodies and for the development of rotavirus vaccines.

AB - A P[6]G9 group-A rotavirus caused a protracted hospital outbreak of neonatal diarrhoea in The Netherlands. The outbreak lasted 5 months with 52 cases and an average attack rate of 40%, 46 cases were in an incubator section for neonates under 1 month of age. Rotavirus P161G9 was detected by RT-PCR in stool samples from the 31 cases tested. Emergence of this genotype in Europe may have implications for neonates lacking protective maternal antibodies and for the development of rotavirus vaccines.

KW - Cross Infection/diagnosis

KW - Diarrhea, Infantile/diagnosis

KW - Disease Outbreaks

KW - Feces/virology

KW - Female

KW - Genotype

KW - Humans

KW - Infant, Newborn

KW - Latex Fixation Tests

KW - Male

KW - Netherlands/epidemiology

KW - Rotavirus/genetics

KW - Rotavirus Infections/diagnosis

U2 - 10.1016/S0140-6736(00)02760-4

DO - 10.1016/S0140-6736(00)02760-4

M3 - A1: Web of Science-article

C2 - 11030297

SN - 0140-6736

VL - 356

SP - 1161

EP - 1162

JO - Lancet

JF - Lancet

IS - 9236

ER -

Emerging group-A rotavirus and a nosocomial outbreak of diarrhoea

Abstract

Keywords

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